ARN14974
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555389

CAS#: 1644158-57-5

Description: ARN14974 is a benzoxazolone carboxamide inhibitor of acid ceramidase (IC50 = 79 nM).


Chemical Structure

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ARN14974
CAS# 1644158-57-5

Theoretical Analysis

MedKoo Cat#: 555389
Name: ARN14974
CAS#: 1644158-57-5
Chemical Formula: C24H21FN2O3
Exact Mass: 404.15
Molecular Weight: 404.441
Elemental Analysis: C, 71.27; H, 5.23; F, 4.70; N, 6.93; O, 11.87

Price and Availability

Size Price Availability Quantity
500mg USD 2050
1g USD 3250
2g USD 5750
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Synonym: ARN14974; ARN-14974; ARN 14974; Acid Ceramidase Inhibitor 17a;

IUPAC/Chemical Name: 6-(4-fluorophenyl)-2-oxo-N-(4-phenylbutyl)-3(2H)-benzoxazolecarboxamide

InChi Key: DPYVAZSLMQCVOG-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H21FN2O3/c25-20-12-9-18(10-13-20)19-11-14-21-22(16-19)30-24(29)27(21)23(28)26-15-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-14,16H,4-5,8,15H2,(H,26,28)

SMILES Code: O=C(N1C(OC2=CC(C3=CC=C(F)C=C3)=CC=C12)=O)NCCCCC4=CC=CC=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 404.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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