WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 564669
CAS#: 1631-28-3
Description: p-Tolylmaleimide is a water channel inhibitor which binds to aquaporin Z (AqpZ).
MedKoo Cat#: 564669
Name: p-Tolylmaleimide
CAS#: 1631-28-3
Chemical Formula: C11H9NO2
Exact Mass: 187.0633
Molecular Weight: 187.2
Elemental Analysis: C, 70.58; H, 4.85; N, 7.48; O, 17.09
Synonym: p Tolylmaleimide; pTolylmaleimide; p-Tolylmaleimide
IUPAC/Chemical Name: 1-(4-Methylphenyl)-1{H}-pyrrole-2,5-dione; 1-(p-tolyl)-1H-pyrrole-2,5-dione
InChi Key: KCFXNGDHQPMIAQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H9NO2/c1-8-2-4-9(5-3-8)12-10(13)6-7-11(12)14/h2-7H,1H3
SMILES Code: CC1=CC=C(N2C(C=CC2=O)=O)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 187.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Imoto H, Kizaki K, Watase S, Matsukawa K, Naka K. Color Tuning of the Aggregation-Induced Emission of Maleimide Dyes by Molecular Design and Morphology Control. Chemistry. 2015 Aug 17;21(34):12105-11. doi: 10.1002/chem.201501519. Epub 2015 Jul 14. PubMed PMID: 26179252.
