WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 584710
Description: Mazethramycin is an anthramycin group antibiotic that is isolated from Streptomyces thioluteus ME561.
MedKoo Cat#: 584710
Chemical Formula: C17H19N3O4
Exact Mass: 329.1376
Molecular Weight: 329.356
Elemental Analysis: C, 62.00; H, 5.81; N, 12.76; O, 19.43
This product is not in stock, which may be available by custom synthesis.
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Synonym: Mazethramycin; Mezethramycin A
IUPAC/Chemical Name: 2-Propenamide, N-methyl-3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-
InChi Key: PRRWHBNSRJELFG-GQCTYLIASA-N
InChi Code: InChI=1S/C17H19N3O4/c1-9-3-5-11-14(15(9)22)19-16(23)12-7-10(4-6-13(21)18-2)8-20(12)17(11)24/h3-6,8,12,16,19,22-23H,7H2,1-2H3,(H,18,21)/b6-4+
SMILES Code: O=C(NC)/C=C/C(C1)=CN2C1C(O)NC3=C(O)C(C)=CC=C3C2=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 329.356 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kunimoto S, Masuda T, Kanbayashi N, Hamada M, Naganawa H, Miyamoto M, Takeuchi T, Umezawa H. Mazethramycin, a new member of anthramycin group antibiotics. J Antibiot (Tokyo). 1980 Jun;33(6):665-7. PubMed PMID: 7419478.
2: Ishizuka M. [Immunomodulation by antitumor antibiotics]. Gan To Kagaku Ryoho. 1986 Mar;13(3 Pt 2):697-700. Japanese. PubMed PMID: 3963840.