Falcarinol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564520

CAS#: 81203-57-8

Description: Falcarinol is the most potent antiplatelet agent in ginseng, and it inhibits thromboxane formation.


Chemical Structure

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Falcarinol
CAS# 81203-57-8

Theoretical Analysis

MedKoo Cat#: 564520
Name: Falcarinol
CAS#: 81203-57-8
Chemical Formula: C17H24O
Exact Mass: 244.1827
Molecular Weight: 244.38
Elemental Analysis: C, 83.55; H, 9.90; O, 6.55

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Panaxynol, (+)-Falcarinol, (+) Falcarinol, Falcarinol

IUPAC/Chemical Name: (3S,9Z)-heptadeca-1,9-dien-4,6-diyn-3-ol

InChi Key: UGJAEDFOKNAMQD-DVQDXYAYSA-N

InChi Code: InChI=1S/C17H24O/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17(18)4-2/h4,10-11,17-18H,2-3,5-9,12H2,1H3/b11-10+/t17-/m0/s1

SMILES Code: C=C[C@H](O)C#CC#CC/C=C/CCCCCCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 244.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Stefanson AL, Bakovic M. Falcarinol Is a Potent Inducer of Heme Oxygenase-1 and Was More Effective than Sulforaphane in Attenuating Intestinal Inflammation at Diet-Achievable Doses. Oxid Med Cell Longev. 2018 Oct 21;2018:3153527. doi: 10.1155/2018/3153527. eCollection 2018. PubMed PMID: 30420908; PubMed Central PMCID: PMC6215554.

2: Busta L, Yim W, LaBrant EW, Wang P, Grimes L, Malyszka K, Cushman JC, Santos P, Kosma DK, Cahoon EB. Identification of genes encoding enzymes catalyzing the early steps of carrot polyacetylene biosynthesis. Plant Physiol. 2018 Oct 17. pii: pp.01195.2018. doi: 10.1104/pp.18.01195. [Epub ahead of print] PubMed PMID: 30333150.

3: Kobaek-Larsen M, Nielsen DS, Kot W, Krych Ł, Christensen LP, Baatrup G. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer. BMC Res Notes. 2018 Jun 27;11(1):411. doi: 10.1186/s13104-018-3527-y. PubMed PMID: 29945666; PubMed Central PMCID: PMC6020439.

4: Medbouhi A, Merad N, Khadir A, Bendahou M, Djabou N, Costa J, Muselli A. Chemical Composition and Biological Investigations of Eryngium triquetrum Essential Oil from Algeria. Chem Biodivers. 2018 Jan;15(1). doi: 10.1002/cbdv.201700343. Epub 2017 Dec 27. PubMed PMID: 29083533.

5: Kobaek-Larsen M, El-Houri RB, Christensen LP, Al-Najami I, Fretté X, Baatrup G. Dietary polyacetylenes, falcarinol and falcarindiol, isolated from carrots prevents the formation of neoplastic lesions in the colon of azoxymethane-induced rats. Food Funct. 2017 Mar 22;8(3):964-974. doi: 10.1039/c7fo00110j. PubMed PMID: 28197615.