Zygosporin D

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MedKoo CAT#: 581596

CAS#: 25374-67-8

Description: Zygosporin D is one of the cytochalasins was isolated from the culture filtrate of the fungus Metarrhizium anisopliae.

Chemical Structure

Zygosporin D
CAS# 25374-67-8

Theoretical Analysis

MedKoo Cat#: 581596
Name: Zygosporin D
CAS#: 25374-67-8
Chemical Formula: C28H35NO5
Exact Mass: 465.25
Molecular Weight: 465.590
Elemental Analysis: C, 72.23; H, 7.58; N, 3.01; O, 17.18

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: Zygosporin D; Deactylzygosporin A; Zygosporin D.

IUPAC/Chemical Name: (3R,3aS,4S,6S,6aR,7E,10S,12R,13Z,15R,15aS)-3-benzyl-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-3,3a,4,5,6,6a,9,10,12,15-decahydro-1H-cycloundeca[d]isoindole-1,11(2H)-dione


InChi Code: InChI=1S/C28H35NO5/c1-16-9-8-12-20-24(31)18(3)17(2)23-21(15-19-10-6-5-7-11-19)29-26(33)28(20,23)22(30)13-14-27(4,34)25(16)32/h5-8,10-14,16-17,20-24,30-31,34H,3,9,15H2,1-2,4H3,(H,29,33)/b12-8+,14-13-/t16-,17+,20-,21+,22+,23+,24+,27+,28-/m0/s1

SMILES Code: C1([C@@]23[C@H]([C@@H](Cc4ccccc4)N1)[C@@H](C(=C)[C@H]([C@@H]2C=CC[C@H](C)C([C@](C=C[C@H]3O)(C)O)=O)O)C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 465.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Li XG, Pan WD, Zhang XJ, Xiao JH. [Antitumor Chemical Entities of Cordyceps taii Mycelia Powder from Guizhou]. Zhong Yao Cai. 2015 Oct;38(10):2083-6. Chinese. PubMed PMID: 27254919.

2: Fujii Y, Tani H, Ichinoe M, Nakajima H. Zygosporin D and two new cytochalasins produced by the fungus Metarrhizium anisopliae. J Nat Prod. 2000 Jan;63(1):132-5. PubMed PMID: 10650095.

3: Betina V, Janstová D, Spisiaková J. Effects of antibiotics on the life cycle of Neurospora crassa. Folia Microbiol (Praha). 1975;20(4):340-5. PubMed PMID: 51812.

4: Aldridge DC, Turner WB. The identity of zygosporin A and cytochalasin D. J Antibiot (Tokyo). 1969 Apr;22(4):170. PubMed PMID: 5800426.