MAO-B inhibitor C5

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564407

CAS#: 1230-77-9

Description: MAO-B inhibitor C5 is a potent and selective MAO-B inhibitor.

Chemical Structure

MAO-B inhibitor C5
CAS# 1230-77-9

Theoretical Analysis

MedKoo Cat#: 564407
Name: MAO-B inhibitor C5
CAS#: 1230-77-9
Chemical Formula: C18H19NO2
Exact Mass: 281.1416
Molecular Weight: 281.36
Elemental Analysis: C, 76.84; H, 6.81; N, 4.98; O, 11.37

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: MAO-B inhibitor C-5; MAO-B inhibitor-C5; MAO-B inhibitor C5

IUPAC/Chemical Name: (2E)-3-[4-(Dimethylamino) phenyl]-1-(4-methoxyphenyl) prop-2-en-1-one


InChi Code: InChI=1S/C18H19NO2/c1-19(2)16-9-4-14(5-10-16)6-13-18(20)15-7-11-17(21-3)12-8-15/h4-13H,1-3H3/b13-6+

SMILES Code: O=C(C1=CC=C(OC)C=C1)/C=C/C2=CC=C(N(C)C)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 281.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Mathew B, Mathew GE, Ucar G, Joy M, Nafna EK, Lohidakshan KK, Suresh J. Monoamine oxidase inhibitory activity of methoxy-substituted chalcones. Int J Biol Macromol. 2017 Nov;104(Pt A):1321-1329. doi: 10.1016/j.ijbiomac.2017.05.162. Epub 2017 Jun 1. PubMed PMID: 28577983.

2: Zarmouh NO, Messeha SS, Elshami FM, Soliman KF. Evaluation of the Isoflavone Genistein as Reversible Human Monoamine Oxidase-A and -B Inhibitor. Evid Based Complement Alternat Med. 2016;2016:1423052. doi: 10.1155/2016/1423052. Epub 2016 Mar 28. PubMed PMID: 27118978; PubMed Central PMCID: PMC4826920.

3: Mostert S, Petzer A, Petzer JP. Indanones as high-potency reversible inhibitors of monoamine oxidase. ChemMedChem. 2015 May;10(5):862-73. doi: 10.1002/cmdc.201500059. Epub 2015 Mar 27. PubMed PMID: 25820651.