WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564327

CAS#: 2230044-57-0

Description: MB710 is a Y220C stabilizer which stabilizes the thermolabile p53 cancer mutant Y220C and shows anticancer activity in p53-Y220C cell lines.

Chemical Structure

CAS# 2230044-57-0

Theoretical Analysis

MedKoo Cat#: 564327
Name: MB710
CAS#: 2230044-57-0
Chemical Formula: C16H16IN3O3S
Exact Mass: 456.9957
Molecular Weight: 457.29
Elemental Analysis: C, 42.03; H, 3.53; I, 27.75; N, 9.19; O, 10.50; S, 7.01

Price and Availability

Size Price Availability Quantity
5.0mg USD 850.0 2 Weeks
10.0mg USD 1450.0 2 Weeks
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Synonym: MB-710; MB 710; MB710

IUPAC/Chemical Name: 2-(Diethylamino)-5-hydroxy-6-iodo-7-(1H-pyrrol-1-yl)benzo[d]thiazole-4-carboxylic acid


InChi Code: InChI=1S/C16H16IN3O3S/c1-3-19(4-2)16-18-11-9(15(22)23)13(21)10(17)12(14(11)24-16)20-7-5-6-8-20/h5-8,21H,3-4H2,1-2H3,(H,22,23)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 457.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Baud MGJ, Bauer MR, Verduci L, Dingler FA, Patel KJ, Horil Roy D, Joerger AC, Fersht AR. Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines. Eur J Med Chem. 2018 May 25;152:101-114. doi: 10.1016/j.ejmech.2018.04.035. Epub 2018 Apr 21. PubMed PMID: 29702446; PubMed Central PMCID: PMC5986712.


5.0mg / USD 850.0