NUCC-474

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MedKoo CAT#: 564314

CAS#: NONE

Description: NUCC-474 is a potent activin antagonist.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-03. Prices are subject to change without notice.

NUCC-474 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564314
Name: NUCC-474
CAS#: NONE
Chemical Formula: C22H32N2O3S
Exact Mass: 404.2134
Molecular Weight: 404.57
Elemental Analysis: C, 65.31; H, 7.97; N, 6.92; O, 11.86; S, 7.92


Synonym: NUCC474; NUCC 474; NUCC-474

IUPAC/Chemical Name: (S)-3-(1-((5-(3-hydroxy-3-methylbut-1-yn-1-yl)thiophen-2-yl)methyl)piperidin-3-yl)-1-morpholinopropan-1-one

InChi Key: PKJPRVVIATWBDB-SFHVURJKSA-N

InChi Code: InChI=1S/C22H32N2O3S/c1-22(2,26)10-9-19-6-7-20(28-19)17-23-11-3-4-18(16-23)5-8-21(25)24-12-14-27-15-13-24/h6-7,18,26H,3-5,8,11-17H2,1-2H3/t18-/m0/s1

SMILES Code: O=C(N1CCOCC1)CC[C@H]2CN(CC3=CC=C(C#CC(C)(O)C)S3)CCC2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Zhu J, Mishra RK, Schiltz GE, Makanji Y, Scheidt KA, Mazar AP, Woodruff TK. Virtual High-Throughput Screening To Identify Novel Activin Antagonists. J Med Chem. 2015 Jul 23;58(14):5637-48. doi: 10.1021/acs.jmedchem.5b00753. Epub 2015 Jul 7. PubMed PMID: 26098096; PubMed Central PMCID: PMC4635973.