NC2213

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MedKoo CAT#: 564299

CAS#: NONE

Description: NC2213 is an inhibitor of methionine aminopeptidase 2 (MetAP2).


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-30. Prices are subject to change without notice.

NC2213 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564299
Name: NC2213
CAS#: NONE
Chemical Formula: C24H27N3O11S2
Exact Mass:
Molecular Weight: 597.61
Elemental Analysis: C, 48.24; H, 4.55; N, 7.03; O, 29.45; S, 10.73


Synonym: NC-2213; NC 2213; NC2213

IUPAC/Chemical Name: 2-((3-(3,5-bis((E)-4-nitrobenzylidene)-4-oxopiperidin-1-yl)-3-oxopropyl)thio)ethane-1-sulfonic acid dihydrate

InChi Key: ABOORZPMWQNZAY-HPKCLRQXSA-N

InChi Code: InChI=1S/C24H23N3O9S2.2H2O/c28-23(9-10-37-11-12-38(34,35)36)25-15-19(13-17-1-5-21(6-2-17)26(30)31)24(29)20(16-25)14-18-3-7-22(8-4-18)27(32)33;;/h1-8,13-14H,9-12,15-16H2,(H,34,35,36);2*1H2/b19-13+,20-14+;;

SMILES Code: O=S(CCSCCC(N1C/C(C(/C(C1)=C/C2=CC=C([N+]([O-])=O)C=C2)=O)=C\C3=CC=C([N+]([O-])=O)C=C3)=O)(O)=O.[H]O[H].[H]O[H]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Selvakumar P, Lakshmikuttyamma A, Das U, Pati HN, Dimmock JR, Sharma RK. NC2213: a novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells. Mol Cancer. 2009 Aug 24;8:65. doi: 10.1186/1476-4598-8-65. PubMed PMID: 19703310; PubMed Central PMCID: PMC2740849.