Nexinhib20
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MedKoo CAT#: 584635

CAS#: 331949-35-0

Description: Nexinhib20 is a Rab27 inhibitor that inhibits neutrophil exocytosis and is active in vivo.


Price and Availability

Size Price Shipping out time Quantity
5mg USD 250 2 Weeks
25mg USD 560 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-22. Prices are subject to change without notice.

Nexinhib20, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 584635
Name: Nexinhib20
CAS#: 331949-35-0
Chemical Formula: C15H16N4O3
Exact Mass: 300.1222
Molecular Weight: 300.318
Elemental Analysis: C, 59.99; H, 5.37; N, 18.66; O, 15.98


Synonym: Nexinhib20

IUPAC/Chemical Name: 4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-penten-3-one

InChi Key: VKSOIYNNOFGGES-JYRVWZFOSA-N

InChi Code: InChI=1S/C15H16N4O3/c1-15(2,3)14(20)13(18-10-16-9-17-18)8-11-5-4-6-12(7-11)19(21)22/h4-10H,1-3H3/b13-8-

SMILES Code: CC(C)(C)C(/C(N1N=CN=C1)=C/C2=CC=CC([N+]([O-])=O)=C2)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

Johnson et al (2016) Identification of neutrophil exocytosis inhibitors (Nexinhibs), small molecule inhibitors of neutrophil exocytosis and inflammation: druggability of the small GTPase Rab27a. J.Biol.Chem. 291 25965 PMID: 27702998