WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573116

CAS#: 251908-92-6

Description: AM-1172 is an endocannabinoid analog specifically designed to be a potent and selective inhibitor of AEA uptake that is resistant to FAAH hydrolysis.

Chemical Structure

CAS# 251908-92-6

Theoretical Analysis

MedKoo Cat#: 573116
Name: AM-1172
CAS#: 251908-92-6
Chemical Formula: C27H39NO2
Exact Mass: 409.2981
Molecular Weight: 409.61
Elemental Analysis: C, 79.17; H, 9.60; N, 3.42; O, 7.81

Price and Availability

Size Price Availability Quantity
5.0mg USD 250.0 2 Weeks
10.0mg USD 425.0 2 Weeks
50.0mg USD 1010.0 2 Weeks
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Synonym: AM-1172

IUPAC/Chemical Name: N-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yl-4-hydroxybenzamide


InChi Code: 1S/C27H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-28-27(30)25-20-22-26(29)23-21-25/h6-7,9-10,12-13,15-16,20-23,29H,2-5,8,11,14,17-19,24H2,1H3,(H,28,30)/b7-6-,10-9-,13-12-,16-15-

SMILES Code: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCNC(=O)c1ccc(O)cc1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 409.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Tutka P, Wlaź A, Florek-Łuszczki M, Kołodziejczyk P, Bartusik-Aebisher D, Łuszczki JJ. Arvanil, olvanil, AM 1172 and LY 2183240 (various cannabinoid CB1 receptor agonists) increase the threshold for maximal electroshock-induced seizures in mice. Pharmacol Rep. 2018 Feb;70(1):106-109. doi: 10.1016/j.pharep.2017.08.006. Epub 2017 Aug 24. PubMed PMID: 29335158.

2: Hillard CJ, Shi L, Tuniki VR, Falck JR, Campbell WB. Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. J Mol Neurosci. 2007 Sep;33(1):18-24. PubMed PMID: 17901541; PubMed Central PMCID: PMC2248273.

3: Kaczocha M, Hermann A, Glaser ST, Bojesen IN, Deutsch DG. Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. J Biol Chem. 2006 Apr 7;281(14):9066-75. Epub 2006 Feb 6. PubMed PMID: 16461355.

4: Glaser ST, Kaczocha M, Deutsch DG. Anandamide transport: a critical review. Life Sci. 2005 Aug 19;77(14):1584-604. Review. PubMed PMID: 15979096.

5: Fegley D, Kathuria S, Mercier R, Li C, Goutopoulos A, Makriyannis A, Piomelli D. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8756-61. Epub 2004 May 11. PubMed PMID: 15138300; PubMed Central PMCID: PMC423268.


5.0mg / USD 250.0