WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564244


Description: 680SIR is a fluorescent probe for near-IR live-cell super-resolution imaging.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564244
Name: 680SIR
Chemical Formula: C35H36N2O4Si
Exact Mass: 576.2444
Molecular Weight: 576.77
Elemental Analysis: C, 72.89; H, 6.29; N, 4.86; O, 11.10; Si, 4.87

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Si-rhodamine 680SiR; 680-SIR; 680 SIR; 680SIR

IUPAC/Chemical Name: 3a,12a-Diaza-16,16-dimethyl-3'-oxo-2,3,3a,4,5,6,10,11,12,12a,13,14,15,16-tetradecahydro-1H,3'H-spiro[diphenaleno[1,2-b:2',1'-e]siline-8,1'-isobenzofuran]-6'-carboxylic acid


InChi Code: InChI=1S/C35H36N2O4Si/c1-42(2)31-24-9-5-15-36-13-3-7-20(29(24)36)17-27(31)35(26-19-22(33(38)39)11-12-23(26)34(40)41-35)28-18-21-8-4-14-37-16-6-10-25(30(21)37)32(28)42/h11-12,17-19H,3-10,13-16H2,1-2H3,(H,38,39)

SMILES Code: O=C(C1=CC(C2(C3=C4)C5=CC(CCCN6CCC7)=C6C7=C5[Si](C)(C)C3=C8CCCN9CCCC4=C89)=C(C=C1)C(O2)=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 576.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Butkevich AN, Ta H, Ratz M, Stoldt S, Jakobs S, Belov VN, Hell SW. Two-Color 810 nm STED Nanoscopy of Living Cells with Endogenous SNAP-Tagged Fusion Proteins. ACS Chem Biol. 2018 Feb 16;13(2):475-480. doi: 10.1021/acschembio.7b00616. Epub 2017 Oct 2. PubMed PMID: 28933823.