Obidoxime sulfate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527969

CAS#: 73840-43-4 (sulfate)

Description: Obidoxime sulfate is an agricultural chemical.


Chemical Structure

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Obidoxime sulfate
CAS# 73840-43-4 (sulfate)

Theoretical Analysis

MedKoo Cat#: 527969
Name: Obidoxime sulfate
CAS#: 73840-43-4 (sulfate)
Chemical Formula: C14H16N4O10S2
Exact Mass: 464.0308
Molecular Weight: 464.42
Elemental Analysis: C, 36.21; H, 3.47; N, 12.06; O, 34.45; S, 13.81

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 2337-82-8 (Br)   73840-43-4 (sulfate)   4605-73-6 (iodide)   114-90-9 (Cl)  

Synonym: Obidoxime sulfate

IUPAC/Chemical Name: Pyridinium, 1,1'-(oxydimethylene)bis(4-formyl-, disulfate, dioxime

InChi Key: HBBXRXJROXBWSA-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H14N4O3.H2O7S2/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;1-8(2,3)7-9(4,5)6/h1-10H,11-12H2;(H,1,2,3)(H,4,5,6)

SMILES Code: O/N=C/C1=CC=[N+](COC[N+]2=CC=C(/C=N/O)C=C2)C=C1.[O-]S(=O)(OS(=O)([O-])=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 464.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Joosen MJA, Klaassen SD, Verheij E, van Groningen T, Cornelissen AS, Skiadopoulos MH, Cochrane L, Shearer JD. Efficacy of atropine sulfate/obidoxime chloride co-formulation against sarin exposure in guinea pigs. Chem Biol Interact. 2018 Sep 12;296:34-42. doi: 10.1016/j.cbi.2018.09.004. [Epub ahead of print] PubMed PMID: 30217478.

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3: Sharma R, Gupta PK, Mazumder A, Dubey DK, Ganesan K, Vijayaraghavan R. A quantitative NMR protocol for the simultaneous analysis of atropine and obidoxime in parenteral injection devices. J Pharm Biomed Anal. 2009 May 1;49(4):1092-6. doi: 10.1016/j.jpba.2009.01.035. Epub 2009 Feb 6. PubMed PMID: 19299099.

4: Pajoumand A, Shadnia S, Rezaie A, Abdi M, Abdollahi M. Benefits of magnesium sulfate in the management of acute human poisoning by organophosphorus insecticides. Hum Exp Toxicol. 2004 Dec;23(12):565-9. PubMed PMID: 15688984.

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6: Lifshitz M, Rotenberg M, Sofer S, Tamiri T, Shahak E, Almog S. Carbamate poisoning and oxime treatment in children: a clinical and laboratory study. Pediatrics. 1994 Apr;93(4):652-5. PubMed PMID: 8134223.

7: Clement JG. Toxicity of the combined nerve agents GB/GF in mice: efficacy of atropine and various oximes as antidotes. Arch Toxicol. 1994;68(1):64-6. PubMed PMID: 8166607.

8: Prandota J, Nienartowicz B, Nowicka J. [Dramatic course of poisoning with a organophosphate compound in a 4-year-old boy treated with obidoxime chloride and atropine sulfate]. Pediatr Pol. 1982 Nov;57(11):975-9. Polish. PubMed PMID: 6763186.

9: Brüner H, Gandawidjaja L, Hettwer H, Oldiges H. [Possible combinations of antidotal therapy in rats following intoxication with phosphoric acid esters (author's transl)]. Arzneimittelforschung. 1977;27(10):1983-8. German. PubMed PMID: 336055.