Obidoxime iodide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527968

CAS#: 4605-73-6 (iodide)

Description: Obidoxime iodide is an agricultural chemical.


Chemical Structure

img
Obidoxime iodide
CAS# 4605-73-6 (iodide)

Theoretical Analysis

MedKoo Cat#: 527968
Name: Obidoxime iodide
CAS#: 4605-73-6 (iodide)
Chemical Formula: C14H16I2N4O3
Exact Mass: 541.9312
Molecular Weight: 542.1159
Elemental Analysis: C, 31.02; H, 2.98; I, 46.82; N, 10.34; O, 8.85

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 2337-82-8 (Br)   73840-43-4 (sulfate)   4605-73-6 (iodide)   114-90-9 (Cl)  

Synonym: Obidoxime iodide

IUPAC/Chemical Name: 1,1'-(Oxydimethylene)bis(4-formylpyridinium) diiodide dioxime

InChi Key: MLAAVDSBLFBFQX-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H14N4O3.2HI/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H

SMILES Code: O/N=C/C1=CC=[N+](COC[N+]2=CC=C(/C=N/O)C=C2)C=C1.[I-].[I-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 542.1159 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Niessen KV, Seeger T, Rappenglück S, Wein T, Höfner G, Wanner KT, Thiermann H, Worek F. In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers. Toxicol Lett. 2018 Sep 1;293:190-197. doi: 10.1016/j.toxlet.2017.10.009. Epub 2017 Oct 10. PubMed PMID: 29024789.

2: Niessen KV, Seeger T, Tattersall JE, Timperley CM, Bird M, Green C, Thiermann H, Worek F. Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length. Chem Biol Interact. 2013 Dec 5;206(3):545-54. doi: 10.1016/j.cbi.2013.10.012. Epub 2013 Oct 21. PubMed PMID: 24157926.

3: Jun D, Kuca K, Picha J, Koleckar V, Marek J. Potency of novel oximes to reactivate sarin inhibited human cholinesterases. Drug Chem Toxicol. 2008;31(1):1-9. PubMed PMID: 18161504.

4: Zhang YH, Miyata T, Wu ZJ, Wu G, Xie LH. Hydrolysis of acetylthiocholine iodide and reactivation of phoxim-inhibited acetylcholinesterase by pralidoxime chloride, obidoxime chloride and trimedoxime. Arch Toxicol. 2007 Nov;81(11):785-92. Epub 2007 May 30. PubMed PMID: 17534602.

5: Racakova V, Hrabinova M, Jun D, Kuca K. Substituted monoquaternary oximes as reactivators of cyclosarin--and chlorpyrifos--inhibited acetylcholinesterase. Arh Hig Rada Toksikol. 2006 Dec;57(4):387-90. PubMed PMID: 17265677.

6: Worek F, Eyer P. The liberation of thiocholine from acetylthiocholine (ASCh) by pralidoxime iodide (2=PAM) and other oximes (obidoxime and diacetylmonoxime). Toxicol Lett. 2006 Dec 15;167(3):256-7; author reply 258. Epub 2006 Oct 20. PubMed PMID: 17113251.

7: Sakurada K, Ikegaya H, Ohta H, Akutsu T, Takatori T. Hydrolysis of an acetylthiocholine by pralidoxime iodide (2-PAM). Toxicol Lett. 2006 Oct 25;166(3):255-60. Epub 2006 Aug 12. PubMed PMID: 16971069.

8: Das Gupta S, Ghosh AK. Antidotal efficacy of isopropamide iodide in acute fluostigmine poisoning in mice. Pharmazie. 1985 Jul;40(7):499-500. PubMed PMID: 2864706.

9: Ramisz A, Szańkowska Z. Effect of E 600 and Toxobidin on the behavious of cholinesterases in mouse skeletal muscles in the course of experimental trichinellosis. Folia Histochem Cytochem (Krakow). 1976;14(4):321-6. PubMed PMID: 799612.

10: Shlosberg A, Egyed MN, Eilat A, Malkinson M, Preissler E. Efficacy of pralidoxime iodide and obidoxime dichloride as antidotes in diazinon-poisoned goslings. Avian Dis. 1976 Jan-Mar;20(1):162-6. PubMed PMID: 769769.