T-474

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564166

CAS#: NONE

Description: T-474 is a potent dual inhibitor of CDK8 and CDK19. It also inhibits Haspin.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-07-02. Prices are subject to change without notice.

T-474 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564166
Name: T-474
CAS#: NONE
Chemical Formula: C17H16N4O2S
Exact Mass: 340.0994
Molecular Weight: 340.4
Elemental Analysis: C, 59.98; H, 4.74; N, 16.46; O, 9.40; S, 9.42


Synonym: T474; T 474; T-474

IUPAC/Chemical Name: 1-Methyl-8-((2-methylpyridin-3-yl)oxy)-4,5-dihydro-1H-thieno[3,4-g]indazole-6-carboxamide

InChi Key: IUIDISNVIBKQQL-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H16N4O2S/c1-9-12(4-3-7-19-9)23-17-13-11(15(24-17)16(18)22)6-5-10-8-20-21(2)14(10)13/h3-4,7-8H,5-6H2,1-2H3,(H2,18,22)

SMILES Code: O=C(C1=C2CCC3=C(N(C)N=C3)C2=C(OC4=CC=CN=C4C)S1)N


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00