WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564128

CAS#: 92285-87-5

Description: L82-G17 is a selective uncompetitive inhibitor of DNA ligase I (LigI).

Chemical Structure

CAS# 92285-87-5

Theoretical Analysis

MedKoo Cat#: 564128
Name: L82-G17
CAS#: 92285-87-5
Chemical Formula: C11H9ClN4O2
Exact Mass: 264.0414
Molecular Weight: 264.67
Elemental Analysis: C, 49.92; H, 3.43; Cl, 13.39; N, 21.17; O, 12.09

Price and Availability

Size Price Availability Quantity
5.0mg USD 295.0 2 Weeks
10.0mg USD 550.0 2 Weeks
25.0mg USD 950.0 2 Weeks
50.0mg USD 1650.0 2 Weeks
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Synonym: L82-G17; L82G17; L82 G17

IUPAC/Chemical Name: 4-Chloro-5-{2-[(3-hydroxyphenyl)methylidene]hydrazin-1-yl}-2,3-dihydropyridazin-3-one


InChi Code: InChI=1S/C11H9ClN4O2/c12-10-9(6-14-16-11(10)18)15-13-5-7-2-1-3-8(17)4-7/h1-6,17H,(H2,15,16,18)/b13-5+

SMILES Code: O=C1C(Cl)=C(N/N=C/C2=CC=CC(O)=C2)C=NN1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 264.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Howes TRL, Sallmyr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. DNA Repair (Amst). 2017 Dec;60:29-39. doi: 10.1016/j.dnarep.2017.10.002. Epub 2017 Oct 10. Erratum in: DNA Repair (Amst). 2017 Dec 19;:. PubMed PMID: 29078112; PubMed Central PMCID: PMC5881949.


5.0mg / USD 295.0