WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 584592
CAS#: 54848-30-5
Description: Protogracillin is a steroid saponin originally isolated from T. terrestris. It is cytotoxic to K562 cells.
MedKoo Cat#: 584592
Name: Protogracillin
CAS#: 54848-30-5
Chemical Formula: C51H84O23
Exact Mass: 1064.5403
Molecular Weight: 1065.21
Elemental Analysis: C, 57.51; H, 7.95; O, 34.55
Synonym: Protogracillin
IUPAC/Chemical Name: (3beta,22R,25R)-26-(beta-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranoside
InChi Key: GMCGZPQYTRHQRU-DKWQWWTLSA-N
InChi Code: InChI=1S/C51H84O23/c1-20(19-66-45-40(62)38(60)34(56)29(16-52)69-45)8-13-51(65)21(2)32-28(74-51)15-27-25-7-6-23-14-24(9-11-49(23,4)26(25)10-12-50(27,32)5)68-48-44(73-46-41(63)37(59)33(55)22(3)67-46)43(36(58)31(18-54)71-48)72-47-42(64)39(61)35(57)30(17-53)70-47/h6,20-22,24-48,52-65H,7-19H2,1-5H3/t20-,21+,22+,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34-,35-,36-,37-,38+,39+,40-,41-,42-,43+,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1
SMILES Code: O[C@H]([C@@H](CO)O1)[C@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)[C@@H](O[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)[C@@H]1O[C@H]4CC[C@]5(C)[C@@]6([H])CC[C@]7(C)[C@]8([H])[C@@]([H])(O[C@@](CC[C@@H](C)CO[C@H]9[C@@H]([C@H]([C@@H]([C@@H](CO)O9)O)O)O)(O)[C@H]8C)C[C@@]7([H])[C@]6([H])CC=C5C4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 1065.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Tomova, M., Gyulemetova, R., Zarkova, S., et al. Steroidal saponins from Tribulus terrestris L. with a stimulating action on the sexual functions. 1st Int. Conf. Chem. Biotechnol. Biol. Act. Nat. Prod. 3(1), 298-302 (1982).
2. Hu, K., Dong, A.-J., Yao, X.-S., et al. Antineoplastic steroidal saponins from rhizomes of DIoscorea collettii var. Hypoglauca. Stud. Plant Sci. 6, 220-229 (1999).
