NEU617

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MedKoo CAT#: 564049

CAS#: 1432450-82-2

Description: NEU617 is an inhibitor of the growth of protozoan parasites, against T. brucei bloodstream proliferation.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-31. Prices are subject to change without notice.

NEU617 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564049
Name: NEU617
CAS#: 1432450-82-2
Chemical Formula: C31H26ClFN4O2
Exact Mass: 540.1728
Molecular Weight: 541.02
Elemental Analysis: C, 68.82; H, 4.84; Cl, 6.55; F, 3.51; N, 10.36; O, 5.91


Synonym: NEU617; NEU 617; NEU-617

IUPAC/Chemical Name: N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-(3-morpholinophenyl)quinazoline-4-amine

InChi Key: FYFNJJQUMONMPL-UHFFFAOYSA-N

InChi Code: InChI=1S/C31H26ClFN4O2/c32-28-18-25(8-10-30(28)39-19-21-3-1-5-24(33)15-21)36-31-27-17-23(7-9-29(27)34-20-35-31)22-4-2-6-26(16-22)37-11-13-38-14-12-37/h1-10,15-18,20H,11-14,19H2,(H,34,35,36)

SMILES Code: FC1=CC(COC2=CC=C(NC3=C4C=C(C5=CC=CC(N6CCOCC6)=C5)C=CC4=NC=N3)C=C2Cl)=CC=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Patel G, Karver CE, Behera R, Guyett PJ, Sullenberger C, Edwards P, Roncal NE, Mensa-Wilmot K, Pollastri MP. Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis. J Med Chem. 2013 May 23;56(10):3820-32. doi: 10.1021/jm400349k. Epub 2013 May 3. PubMed PMID: 23597080; PubMed Central PMCID: PMC3663906.