Lawinal

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584561

CAS#: 55743-09-4

Description: Lawinal is a flavonoid derived from Desmos cochinchinensis Lous that has been shown to have anti-HIV activity.


Chemical Structure

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Lawinal
CAS# 55743-09-4

Theoretical Analysis

MedKoo Cat#: 584561
Name: Lawinal
CAS#: 55743-09-4
Chemical Formula: C17H14O5
Exact Mass: 298.08
Molecular Weight: 298.294
Elemental Analysis: C, 68.45; H, 4.73; O, 26.82

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Lawinal

IUPAC/Chemical Name: 2H-1-Benzopyran-8-carboxaldehyde, 3,4-dihydro-5,7-dihydroxy-6-methyl-4-oxo-2-phenyl-, (S)-

InChi Key: ONESXBRHUWVWFD-ZDUSSCGKSA-N

InChi Code: InChI=1S/C17H14O5/c1-9-15(20)11(8-18)17-14(16(9)21)12(19)7-13(22-17)10-5-3-2-4-6-10/h2-6,8,13,20-21H,7H2,1H3/t13-/m0/s1

SMILES Code: O=CC1=C2C(C(C[C@@H](C3=CC=CC=C3)O2)=O)=C(O)C(C)=C1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 298.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

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Reconstitution Calculator

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1: Joseph CC, Magadula JJ, Nkunya MH. A novel antiplasmodial 3',5'-diformylchalcone and other constituents of Friesodielsia obovata. Nat Prod Res. 2007 Sep;21(11):1009-15. PubMed PMID: 17691050.

2: Ju J, Yu J. [Studies on chemical constituents of seeds of Desmos chinensis Lour]. Zhongguo Zhong Yao Za Zhi. 1999 Jul;24(7):418-21, 446. Chinese. PubMed PMID: 12205876.

3: Liao SX, Han GY, Zhang YR, Zheng QT, He CH. [Studies on the chemical constituents of the root of Desmos cochinchinensis Lour]. Yao Xue Xue Bao. 1989;24(2):110-3. Chinese. PubMed PMID: 2801131.

4: Wu JH, Mao SL, Liao SX, Shi WH, Su ZW, Lan CQ. [Studies on chemical constituents in the root of Desmos grandifolius (I)]. Zhongguo Zhong Yao Za Zhi. 2000 Jul;25(7):419-21. Chinese. PubMed PMID: 12515223.

5: Zhou LD, Yu JG, Guo J, Yang SL. [A-ring formylated flavonoids and oxoaporphinoid alkaloid from Dasymaschalon rostratum Merr. et Chun]. Zhongguo Zhong Yao Za Zhi. 2001 Jan;26(1):39-41. Chinese. PubMed PMID: 12525117.

6: Wu JH, Wang XH, Yi YH, Lee KH. Anti-AIDS agents 54. A potent anti-HIV chalcone and flavonoids from genus Desmos. Bioorg Med Chem Lett. 2003 May 19;13(10):1813-5. PubMed PMID: 12729671.