4-Abza

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563958

CAS#: 95523-13-0

Description: 4-Abza is a potent agonist of A1 adenosine receptors.


Chemical Structure

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4-Abza
CAS# 95523-13-0

Theoretical Analysis

MedKoo Cat#: 563958
Name: 4-Abza
CAS#: 95523-13-0
Chemical Formula: C17H20N6O4
Exact Mass: 372.15
Molecular Weight: 372.390
Elemental Analysis: C, 54.83; H, 5.41; N, 22.57; O, 17.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: 4-Abza; 4Abza; 4 Abza; 4-ABzA; 4ABzA; 4 ABzA; N(6)-(4-aminobenzyl)adenosine

IUPAC/Chemical Name: (2R,3R,4S,5R)-2-[6-[(4-Aminophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChi Key: PMUVNAUPWLXPSA-LSCFUAHRSA-N

InChi Code: InChI=1S/C17H20N6O4/c18-10-3-1-9(2-4-10)5-19-15-12-16(21-7-20-15)23(8-22-12)17-14(26)13(25)11(6-24)27-17/h1-4,7-8,11,13-14,17,24-26H,5-6,18H2,(H,19,20,21)/t11-,13-,14-,17-/m1/s1

SMILES Code: OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NCC4=CC=C(N)C=C4)O1)O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 372.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Munshi R, Linden J. Interaction of purified bovine brain A1-adenosine receptors with guanine nucleotide-binding proteins of human platelet membranes following reconstitution. Mol Pharmacol. 1990 Aug;38(2):170-6. PubMed PMID: 2117248.

2: Leung E, Kwatra MM, Hosey MM, Green RD. Characterization of cardiac A1 adenosine receptors by ligand binding and photoaffinity labeling. J Pharmacol Exp Ther. 1988 Mar;244(3):1150-6. PubMed PMID: 3252029.