WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581322

CAS#: 709-98-8

Description: Propanil is a a widely used herbicide. Propanil is used mainly to control weed growth in rice fields.

Chemical Structure

CAS# 709-98-8

Theoretical Analysis

MedKoo Cat#: 581322
Name: Propanil
CAS#: 709-98-8
Chemical Formula: C15H13Cl2NO
Exact Mass: 293.0374
Molecular Weight: 294.17
Elemental Analysis: C, 61.24; H, 4.45; Cl, 24.10; N, 4.76; O, 5.44

Price and Availability

Size Price Availability Quantity
250.0mg USD 230.0 2 Weeks
10.0g USD 430.0 2 Weeks
100.0g USD 1570.0 2 Weeks
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Synonym: Propanil; Propanex; Propanid; Propanide; Dichloropropionanilide;

IUPAC/Chemical Name: 3',4'-Dichlorophenylpropionanilide


InChi Code: InChI=1S/C15H13Cl2NO/c16-13-8-6-11(10-14(13)17)7-9-15(19)18-12-4-2-1-3-5-12/h1-6,8,10H,7,9H2,(H,18,19)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 294.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Schafer R, Ognibene TJ, Malfatti MA, Turteltaub KW, Barnett JB. Comparative Pharmacokinetics of High and Low Doses of the Herbicide Propanil in Mice. Chem Res Toxicol. 2018 Sep 19. doi: 10.1021/acs.chemrestox.8b00151. [Epub ahead of print] PubMed PMID: 30230318.

2: Hang P, Zhang L, Zhou XY, Hu Q, Jiang JD. Rhizobium album sp. nov., isolated from a propanil-contaminated soil. Antonie Van Leeuwenhoek. 2018 Sep 3. doi: 10.1007/s10482-018-1160-3. [Epub ahead of print] PubMed PMID: 30178161.

3: Carazo-Rojas E, Pérez-Rojas G, Pérez-Villanueva M, Chinchilla-Soto C, Chin-Pampillo JS, Aguilar-Mora P, Alpízar-Marín M, Masís-Mora M, Rodríguez-Rodríguez CE, Vryzas Z. Pesticide monitoring and ecotoxicological risk assessment in surface water bodies and sediments of a tropical agro-ecosystem. Environ Pollut. 2018 Oct;241:800-809. doi: 10.1016/j.envpol.2018.06.020. Epub 2018 Jun 14. PubMed PMID: 29909306.

4: Scholz-Starke B, Bo L, Holbach A, Norra S, Floehr T, Hollert H, Roß-Nickoll M, Schäffer A, Ottermanns R. Simulation-based assessment of the impact of fertiliser and herbicide application on freshwater ecosystems at the Three Gorges Reservoir in China. Sci Total Environ. 2018 Oct 15;639:286-303. doi: 10.1016/j.scitotenv.2018.05.057. Epub 2018 May 20. PubMed PMID: 29791882.

5: Carena L, Proto M, Minella M, Ghigo G, Giovannoli C, Brigante M, Mailhot G, Maurino V, Minero C, Vione D. Evidence of an Important Role of Photochemistry in the Attenuation of the Secondary Contaminant 3,4-Dichloroaniline in Paddy Water. Environ Sci Technol. 2018 Jun 5;52(11):6334-6342. doi: 10.1021/acs.est.8b00710. Epub 2018 May 7. PubMed PMID: 29676902.

6: Zhang L, Wang C, Li Z, Zhao C, Zhang H, Zhang D. Extraction of acetanilides in rice using ionic liquid-based matrix solid phase dispersion-solvent flotation. Food Chem. 2018 Apr 15;245:1190-1195. doi: 10.1016/j.foodchem.2017.11.029. Epub 2017 Nov 10. PubMed PMID: 29287341.

7: Vaz-Moreira I, Narciso-da-Rocha C, Lopes AR, Carvalho G, Lobo-da-Cunha A, Whitman WB, Snauwaert C, Vandamme P, Manaia CM, Nunes OC. Oryzisolibacter propanilivorax gen. nov., sp. nov., a propanil-degrading bacterium. Int J Syst Evol Microbiol. 2017 Oct;67(10):3752-3758. doi: 10.1099/ijsem.0.002184. Epub 2017 Sep 12. PubMed PMID: 28895512.

8: Xu X, Mathieu C, Berthelet J, Duval R, Bui LC, Busi F, Dupret JM, Rodrigues-Lima F. Human Arylamine N-Acetyltransferase 1 Is Inhibited by the Dithiocarbamate Pesticide Thiram. Mol Pharmacol. 2017 Sep;92(3):358-365. doi: 10.1124/mol.117.108662. Epub 2017 Jul 3. PubMed PMID: 28674152.

9: Appah E, Elzey B, Fakayode SO. Investigation of the binding and simultaneous quantifications of propanil and bromoxynil herbicide concentrations in human serum albumin. J Environ Sci Health B. 2017 Jul 3;52(7):495-504. doi: 10.1080/03601234.2017.1303323. Epub 2017 May 25. PubMed PMID: 28541121.

10: Kamireddy K, Matam P, P S P, Parvatam G. Biochemical characterization of a key step involved in 2H4MB production in Decalepis hamiltonii. J Plant Physiol. 2017 Jul;214:74-80. doi: 10.1016/j.jplph.2017.04.006. Epub 2017 Apr 14. PubMed PMID: 28460278.

11: Carena L, Minella M, Barsotti F, Brigante M, Milan M, Ferrero A, Berto S, Minero C, Vione D. Phototransformation of the Herbicide Propanil in Paddy Field Water. Environ Sci Technol. 2017 Mar 7;51(5):2695-2704. doi: 10.1021/acs.est.6b05053. Epub 2017 Feb 21. PubMed PMID: 28145687.

12: Zamani N, Hassanian-Moghaddam H. RE: Methemoglobin measurements are underestimated by the Radical 7 CO-oximeter: experience from a series of moderate to severe propanil poisonings. Clin Toxicol (Phila). 2017 Feb;55(2):157. doi: 10.1080/15563650.2016.1263856. Epub 2016 Dec 6. PubMed PMID: 27921441.

13: Chen Z, Schäffer A. The fate of the herbicide propanil in plants of the littoral zone of the Three Gorges Reservoir (TGR), China. J Environ Sci (China). 2016 Oct;48:24-33. doi: 10.1016/j.jes.2016.01.026. Epub 2016 Apr 23. PubMed PMID: 27745669.

14: Campos M, Karas PS, Perruchon C, Papadopoulou ES, Christou V, Menkissoglou-Spiroudi U, Diez MC, Karpouzas DG. Novel insights into the metabolic pathway of iprodione by soil bacteria. Environ Sci Pollut Res Int. 2017 Jan;24(1):152-163. doi: 10.1007/s11356-016-7682-1. Epub 2016 Oct 5. PubMed PMID: 27704380.

15: Yuan Y, Zhang P, Schäffer A, Schmidt B. 3,4-Dichloroaniline revisited: A study on the fate of the priority pollutant in a sediment-water system derived from a rice growing region in Italy. Sci Total Environ. 2017 Jan 1;574:1012-1020. doi: 10.1016/j.scitotenv.2016.09.099. Epub 2016 Oct 14. PubMed PMID: 27668853.

16: Hulse E, Shihana F, Buckley NA. Methemoglobin measurements are underestimated by the Radical 7 co-oximeter: experience from a series of moderate to severe propanil poisonings. Clin Toxicol (Phila). 2016 Nov;54(9):826-828. Epub 2016 Aug 23. PubMed PMID: 27549603.

17: Shihana F, Dawson AH, Buckley NA. A bedside test for methemoglobinemia, Sri Lanka. Bull World Health Organ. 2016 Aug 1;94(8):622-5. doi: 10.2471/BLT.15.158147. Epub 2016 Jun 14. PubMed PMID: 27516640; PubMed Central PMCID: PMC4969983.

18: Shihana F, Dawson AH, Dobbins T, Dissanayake D, Buckley NA. A bedside test for methaemoglobinemia improved antidote use in propanil poisoning. Clin Toxicol (Phila). 2016 Aug;54(7):576-80. doi: 10.1080/15563650.2016.1177651. Epub 2016 May 19. PubMed PMID: 27196813.

19: Pedroso RM, Al-Khatib K, Alarcón-Reverte R, Fischer AJ. A psbA mutation (Val219 to Ile) causes resistance to propanil and increased susceptibility to bentazon in Cyperus difformis. Pest Manag Sci. 2016 Sep;72(9):1673-80. doi: 10.1002/ps.4267. Epub 2016 Apr 6. PubMed PMID: 26929096.

20: Jayawardena UA, Rohr JR, Navaratne AN, Amerasinghe PH, Rajakaruna RS. Combined Effects of Pesticides and Trematode Infections on Hourglass Tree Frog Polypedates cruciger. Ecohealth. 2016 Mar;13(1):111-22. doi: 10.1007/s10393-016-1103-2. Epub 2016 Feb 24. PubMed PMID: 26911919; PubMed Central PMCID: PMC4852980.


250.0mg / USD 230.0