Febuprol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341373

CAS#: 3102-00-9

Description: Febuprol is a drug from the group of choleretic drugs , that is, it stimulates bile secretion . In addition, it also has spasmolytic (anticonvulsant) and lipid-lowering (lowering blood lipid) properties.

Chemical Structure

img
Febuprol
CAS# 3102-00-9
Instruction

Theoretical Analysis

MedKoo Cat#: 341373
Name: Febuprol
CAS#: 3102-00-9
Chemical Formula: C13H20O3
Exact Mass: 224.14
Molecular Weight: 224.300
Elemental Analysis: C, 69.61; H, 8.99; O, 21.40

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Febuprol ; H-33; H 33; H33; NSC 30151; K-10033; K 10033; K10033.

IUPAC/Chemical Name: 1-Butoxy-3-phenoxy-2-propanol

InChi Key: WBLXZPHICYCDGN-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H20O3/c1-2-3-9-15-10-12(14)11-16-13-7-5-4-6-8-13/h4-8,12,14H,2-3,9-11H2,1H3

SMILES Code: OC(COC1=CC=CC=C1)COCCCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 224.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Jüngst D, Brenner G, Pratschke E, Paumgartner G. Lipid composition and cholesterol nucleation time in gallbladder bile of patients with cholesterol gallstones under choleretic treatment with Febuprol. Z Gastroenterol. 1988 May;26(5):275-8. PubMed PMID: 3407249.

2: Swobodnik W, Wechsler JG, Klüppelberg U, Janowitz P, Hutt V, Ditschuneit H. [Lithogenicity and bile acid pattern in choleretic administration (3-n-butoxy-1-phenoxy-propanol: febuprol) in patients with functional right upper quadrant pain]. Z Gastroenterol. 1987 Nov;25(11):715-20. German. PubMed PMID: 3324520.

3: Ritter U, Kyrein HJ. [Clinical trial of febuprol, a new substance with choleretic activity. Study of efficacy and tolerability]. Arzneimittelforschung. 1983;33(6):891-7. German. PubMed PMID: 6684447.

4: Scholing WE, Weinert W. [Clinical studies on the choleretic agent Febuprol (author's transl)]. MMW Munch Med Wochenschr. 1978 Feb 3;120(5):143-6. German. PubMed PMID: 342924.

5: Eisenburger R. [On the spasmolytic action of 3-butoxy-1-phenoxy-propanol-(2) (febuprol) on the biliary tract (author's transl)]. Arzneimittelforschung. 1977 Jul;27(7):1429-33. German. PubMed PMID: 578468.

6: Wolf C, Ritter U, Zschocke R, Weinert W. [Investigation of the choleretic action of febuprol on healthy test subjects (author's transl)]. MMW Munch Med Wochenschr. 1976 Oct 1;118(40):1285-8. German. PubMed PMID: 824554.

7: Rehm K, hempel K, Maurer-Schultze B, Schlemmer W. [On pharacokinetics and metabolism of the choleretic agent febuprol (author's transl)]. Arzneimittelforschung. 1976;26(5):813-20. German. PubMed PMID: 989353.