U 78753E

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MedKoo CAT#: 581305

CAS#: 67450-78-6

Description: U 78753E is a biochemical.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-09-23. Prices are subject to change without notice.

U 78753E is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 581305
Name: U 78753E
CAS#: 67450-78-6
Chemical Formula: C16H22Cl2N2O
Exact Mass: 328.1109
Molecular Weight: 329.27
Elemental Analysis: Chemical Formula: C16H22Cl2N2O Exact Mass: 328.1109 Molecular Weight: 329.2650 Elemental Analysis: C, 58.37; H, 6.74; Cl, 21.53; N, 8.51; O, 4.86

Synonym: U 78753E; DCDPP; U-78753E; U-78753E;

IUPAC/Chemical Name: N-(2-(Dimethylamino)cyclopentyl)-N-(3,4-dichlorophenyl)propanamid


InChi Code: InChI=1S/C16H22Cl2N2O/c1-4-16(21)20(11-8-9-12(17)13(18)10-11)15-7-5-6-14(15)19(2)3/h8-10,14-15H,4-7H2,1-3H3

SMILES Code: CCC(N(C1C(N(C)C)CCC1)C2=CC=C(Cl)C(Cl)=C2)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Aaron CS, Stankowski LF Jr, Harbach PR, Valencia R, Mayo JK, Mirsalis J, Mazurek JH, Steinmetz KL, Wiser SK, Zimmer DM, et al. Comparative mutagenicity testing of a drug candidate, U-48753E: mechanism of induction of gene mutations in mammalian cells and quantitation of potential hazard. Mutat Res. 1989 Jun;223(2):111-20. PubMed PMID: 2500592.

2: Sethy VH, Day JS, Cooper MM. Dose-dependent down-regulation of beta-adrenergic receptors after chronic intravenous infusion of antidepressants. Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(5):673-82. PubMed PMID: 2851860.

3: Theis DL, Halstead GW, Capponi VJ, Roach BL, Robins RH. Quantitative determination of N-[trans-2-(dimethylamino)-cyclopentyl]-N-(3',4'-dichlorophenyl)propan amide, its 2H5-labeled analogue and their N-dealkylated metabolites in dog serum by capillary gas chromatography-mass spectrometry. J Chromatogr. 1986 Mar 7;375(2):299-311. PubMed PMID: 3700555.

4: Lakings DB, Stryd RP, Gilbertson TJ. Quantitative determination of N-(trans-2-dimethylaminocyclopentyl)-N-(3',4'-dichlorophenyl) propanamide and its N-demethyl metabolite in dog serum by gas chromatography. J Pharm Sci. 1984 Mar;73(3):317-20. PubMed PMID: 6716237.

5: Szmuszkovicz J, Von Voigtlander PF, Kane MP. A new nontricyclic antidepressant agent. Synthesis and activity of N-[trans-2-(dimethylamino)cyclopentyl]-N-(3,4-dichlorophenyl)propanamide and related compounds. J Med Chem. 1981 Oct;24(10):1230-6. PubMed PMID: 7328583.