DB2313 HCl
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MedKoo CAT#: 563801

CAS#: 2170606-75-2 (HCl)

Description: DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets.

Chemical Structure

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DB2313 HCl
CAS# 2170606-75-2 (HCl)
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 563801
Name: DB2313 HCl
CAS#: 2170606-75-2 (HCl)
Chemical Formula: C42H45Cl4FN8O2
Exact Mass: 0.00
Molecular Weight: 854.670
Elemental Analysis: C, 59.02; H, 5.31; Cl, 16.59; F, 2.22; N, 13.11; O, 3.74

Price and Availability

Size Price Availability Quantity
5mg USD 150 Ready to ship
10mg USD 250 Ready to ship
25mg USD 550 Ready to ship
50mg USD 950 Ready to ship
100mg USD 1650 Ready to ship
200mg USD 2650 Ready to ship
500mg USD 3750 Ready to ship
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Related CAS #: 2170606-75-2 (HCl)   2170606-74-1 (free base)    

Synonym: DB2313 HCl; DB 2313 HCl; DB-2313 HCl; DB2313 tetrahydrochloride

IUPAC/Chemical Name: 2,2'-((((2-Fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide) tetrahydrochloride

InChi Key: VTQBTZDMPNTLGK-UHFFFAOYSA-N

InChi Code: InChI=1S/C42H41FN8O2.4ClH/c1-24(2)46-39(44)28-12-18-34-36(20-28)50-41(48-34)26-8-14-32(15-9-26)52-22-30-6-5-7-31(38(30)43)23-53-33-16-10-27(11-17-33)42-49-35-19-13-29(21-37(35)51-42)40(45)47-25(3)4;;;;/h5-21,24-25H,22-23H2,1-4H3,(H2,44,46)(H2,45,47)(H,48,50)(H,49,51);4*1H

SMILES Code: FC1=C(COC2=CC=C(C3=NC4=CC=C(C(NC(C)C)=N)C=C4N3)C=C2)C=CC=C1COC5=CC=C(C6=NC7=CC=C(C(NC(C)C)=N)C=C7N6)C=C5.[H]Cl.[H]Cl.[H]Cl.[H]Cl

Appearance: Solid powder

Purity: >96% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 854.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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