VUN 44557

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 572527

CAS#: 1398044-55-7

Description: VUN 44557, also known as Azido-PEG4-Amido-Tris, also known as Azido-PEG4-Amido-tri-(carboxyethoxymethyl)-methane, is a multi-arm PEG containing an azide group and three hydroxyl groups. The azide group enables Click Chemistry. The indicated molecular weight of the multi-arm PEG is the sum of the molecular weights of all the arms. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digits of its CAS#, according to MedKoo Chemical Nomenclature (

Chemical Structure

VUN 44557
CAS# 1398044-55-7

Theoretical Analysis

MedKoo Cat#: 572527
Name: VUN 44557
CAS#: 1398044-55-7
Chemical Formula: C15H30N4O8
Exact Mass: 394.2064
Molecular Weight: 394.43
Elemental Analysis: C, 45.68; H, 7.67; N, 14.20; O, 32.45

Price and Availability

Size Price Availability Quantity
100.0mg USD 450.0 2 Weeks
250.0mg USD 850.0 2 Weeks
500.0mg USD 1410.0 2 Weeks
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Synonym: Azido-PEG4-Amido-Tris, Azido-PEG4-Amido-tri-(carboxyethoxymethyl)-methane; VUN 44557; VU44557; VUN44557

IUPAC/Chemical Name: 1-azido-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-3,6,9,12-tetraoxapentadecan-15-amide


InChi Code: InChI=1S/C15H30N4O8/c16-19-17-2-4-25-6-8-27-10-9-26-7-5-24-3-1-14(23)18-15(11-20,12-21)13-22/h20-22H,1-13H2,(H,18,23)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 394.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750. PubMed PMID: 27572704; PubMed Central PMCID: PMC5004151.

2: Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MR. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. doi: 10.1016/j.molimm.2013.07.014. Epub 2013 Nov 5. PubMed PMID: 24200843.

3: Garay RP, El-Gewely R, Armstrong JK, Garratty G, Richette P. Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents. Expert Opin Drug Deliv. 2012 Nov;9(11):1319-23. doi: 10.1517/17425247.2012.720969. Epub 2012 Aug 30. PubMed PMID: 22931049.

VUN 44557

100.0mg / USD 450.0