WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563739
CAS#: 73912-52-4
Description: MS0015203 is a potent and selective agonist of the neuropeptide receptor GPR171.
MedKoo Cat#: 563739
Name: MS0015203
CAS#: 73912-52-4
Chemical Formula: C12H11NO5
Exact Mass: 249.0637
Molecular Weight: 249.22
Elemental Analysis: C, 57.83; H, 4.45; N, 5.62; O, 32.10
Synonym: MS0015203; MS-0015203; MS 0015203;
IUPAC/Chemical Name: 5-[(2-Methyl-1-oxo-2-propen-1-yl)amino]-1,3-benzenedicarboxylic acid
InChi Key: NVOBVSWSDYFEMR-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H11NO5/c1-6(2)10(14)13-9-4-7(11(15)16)3-8(5-9)12(17)18/h3-5H,1H2,2H3,(H,13,14)(H,15,16)(H,17,18)
SMILES Code: O=C(C1=CC(NC(C(C)=C)=O)=CC(C(O)=O)=C1)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 249.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Wardman JH, Gomes I, Bobeck EN, Stockert JA, Kapoor A, Bisignano P, Gupta A, Mezei M, Kumar S, Filizola M, Devi LA. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Sci Signal. 2016 May 31;9(430):ra55. doi: 10.1126/scisignal.aac8035. PubMed PMID: 27245612; PubMed Central PMCID: PMC5150984.
