ACT-678689
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563700

CAS#: 1783256-96-1

Description: ACT-678689 is a potent inhibitor of tryptophan hydroxylase 1 (TPH1).

Chemical Structure

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ACT-678689
CAS# 1783256-96-1
Instruction

Theoretical Analysis

MedKoo Cat#: 563700
Name: ACT-678689
CAS#: 1783256-96-1
Chemical Formula: C23H22ClFN6O4S2
Exact Mass: 564.08
Molecular Weight: 565.030
Elemental Analysis: C, 48.89; H, 3.92; Cl, 6.27; F, 3.36; N, 14.87; O, 11.33; S, 11.35

Price and Availability

Size Price Availability Quantity
100mg USD 1850 2 Weeks
200mg USD 2450 2 Weeks
500mg USD 3450 2 Weeks
1g USD 4650 2 Weeks
2g USD 6450 2 Weeks
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Synonym: ACT-678689; ACT 678689; ACT678689;

IUPAC/Chemical Name: (S)-N-(6-Chloro-5-{2-[4-(2-fluoro-4-methyl-phenyl)-2-methyl-6,7-dihydro-4H-1-thia-3,3a,5,8-tetraaza-cyclopenta[a]inden-5-yl]-2-oxo-ethoxy}-pyridin-2-yl)-methanesulfonamide

InChi Key: XGWSHBGTWKYXMM-FQEVSTJZSA-N

InChi Code: InChI=1S/C23H22ClFN6O4S2/c1-12-4-5-14(15(25)10-12)20-21-16(26-23-31(21)28-13(2)36-23)8-9-30(20)19(32)11-35-17-6-7-18(27-22(17)24)29-37(3,33)34/h4-7,10,20H,8-9,11H2,1-3H3,(H,27,29)/t20-/m0/s1

SMILES Code: CS(=O)(NC1=NC(Cl)=C(OCC(N2CCC3=C(N4C(SC(C)=N4)=N3)[C@@H]2C5=CC=C(C)C=C5F)=O)C=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 565.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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