Bemitradine
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461871

CAS#: 88133-11-3

Description: Bemitradine is a diuretic antihypertensive agent.


Chemical Structure

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Bemitradine
CAS# 88133-11-3

Theoretical Analysis

MedKoo Cat#: 461871
Name: Bemitradine
CAS#: 88133-11-3
Chemical Formula: C15H17N5O
Exact Mass: 283.14
Molecular Weight: 283.330
Elemental Analysis: C, 63.59; H, 6.05; N, 24.72; O, 5.65

Price and Availability

Size Price Availability Quantity
1mg USD 150 Ready to Ship
5mg USD 550 Ready to Ship
10mg USD 950 Ready to Ship
25mg USD 1650 Ready to Ship
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Synonym: Bemitradine; SC 33643; SC-33643; SC33643;

IUPAC/Chemical Name: 8-(2-ethoxyethyl)-7-phenyl-[1,2,4]triazolo[1,5-c]pyrimidin-5-amine

InChi Key: OZSPQIXKOVJJGE-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H17N5O/c1-2-21-9-8-12-13(11-6-4-3-5-7-11)19-15(16)20-14(12)17-10-18-20/h3-7,10H,2,8-9H2,1H3,(H2,16,19)

SMILES Code: NC1=NC(C2=CC=CC=C2)=C(CCOCC)C3=NC=NN13

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 283.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Gad SC, Burton E, Chengelis CP, Levin S, Piper CE, Oshiro Y, Semler DE. Promotional activities of the non-genotoxic carcinogen bemitradine (SC-33643). J Appl Toxicol. 1992 Jun;12(3):157-64. PubMed PMID: 1629511.

2: Walls CM, Gray A, Vose CW, Robinson Y, Lopez N, Brownsill RD, Steiner JA. Disposition of bemitradine, a renal vasodilator and diuretic, in man. Xenobiotica. 1988 Dec;18(12):1413-23. PubMed PMID: 3245233.

3: Oshiro Y, Balwierz PS, Morris DL, Alden CL, Bunch RT. Morphological transformation of Syrian hamster embryo cells at pH 6.7 by bemitradine, a nongenotoxic carcinogen. In Vitr Mol Toxicol. 2001 Summer;14(2):121-7. PubMed PMID: 11690565.

4: Oshiro Y, Piper CE, Garriott ML, Balwierz PS, Soelter SG, Rohrbacher E. Genetic toxicology studies with a tumor promoter. J Appl Toxicol. 1993 Mar-Apr;13(2):91-101. PubMed PMID: 8486916.

5: Kramer JA, Curtiss SW, Kolaja KL, Alden CL, Blomme EA, Curtiss WC, Davila JC, Jackson CJ, Bunch RT. Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling. Chem Res Toxicol. 2004 Apr;17(4):463-70. PubMed PMID: 15089088.