WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 461836
Description: Sas 1310 is a diltiazem derivative that acts as a calcium antagonist.
MedKoo Cat#: 461836
Name: Sas 1310
Chemical Formula: C26H27N3O4S
Exact Mass: 477.1722
Molecular Weight: 477.57
Elemental Analysis: C, 65.39; H, 5.70; N, 8.80; O, 13.40; S, 6.71
This product is not in stock, which may be available by custom synthesis.
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Synonym: Sas 1310; Sas-1310;
IUPAC/Chemical Name: 5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl nicotinate
InChi Key: DSYNMAGEJOOLTQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H27N3O4S/c1-28(2)15-16-29-21-8-4-5-9-22(21)34-24(18-10-12-20(32-3)13-11-18)23(25(29)30)33-26(31)19-7-6-14-27-17-19/h4-14,17,23-24H,15-16H2,1-3H3
SMILES Code: O=C(C1=CC=CN=C1)OC2C(C3=CC=C(OC)C=C3)SC4=CC=CC=C4N(CCN(C)C)C2=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 477.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Cargnelli G, Padrini R, Piovan D, Moretto R, Bova S. Effects of SAS 1310, a new calcium antagonist, on isolated myocardial and smooth muscle preparations. Eur J Pharmacol. 1987 Apr 14;136(2):163-70. PubMed PMID: 3595719.