WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 461810
Description: Sarcophytol B is a cembrane-type diterpene isolated from a soft coral, Sarcophyton glaucum.
MedKoo Cat#: 461810
Name: Sarcophytol B
Chemical Formula: C20H32O2
Exact Mass: 304.2402
Molecular Weight: 304.47
Elemental Analysis: C, 78.90; H, 10.59; O, 10.51
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Sarcophytol B; Sarcophytol-B;
IUPAC/Chemical Name: (3E,5Z,9Z,13E)-3-isopropyl-6,10,14-trimethylcyclotetradeca-3,5,9,13-tetraene-1,2-diol
InChi Key: LBNWKNLAXODPTN-URNCNPOUSA-N
InChi Code: InChI=1S/C20H32O2/c1-14(2)18-13-12-16(4)9-6-8-15(3)10-7-11-17(5)19(21)20(18)22/h8,11-14,19-22H,6-7,9-10H2,1-5H3/b15-8-,16-12-,17-11+,18-13+
SMILES Code: OC1C(O)/C(C(C)C)=C/C=C(C)\CC/C=C(C)\CC/C=C1\C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 304.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Fujiki H, Suganuma M, Suguri H, Yoshizawa S, Takagi K, Kobayashi M. Sarcophytols A and B inhibit tumor promotion by teleocidin in two-stage carcinogenesis in mouse skin. J Cancer Res Clin Oncol. 1989;115(1):25-8. PubMed PMID: 2493457.
2: Wright AD, Nielson JL, Tapiolas DM, Liptrot CH, Motti CA. A great barrier reef Sinularia sp. yields two new cytotoxic diterpenes. Mar Drugs. 2012 Aug;10(8):1619-30. Epub 2012 Jul 31. PubMed PMID: 23015765; PubMed Central PMCID: PMC3447330.
3: Fujiki H, Suganuma M, Suguri H, Takagi K, Yoshizawa S, Ootsuyama A, Tanooka H, Okuda T, Kobayashi M, Sugimura T. New antitumor promoters: (-)-epigallocatechin gallate and sarcophytols A and B. Basic Life Sci. 1990;52:205-12. PubMed PMID: 1970233.
4: Sawant SS, Sylvester PW, Avery MA, Desai P, Youssef DT, El Sayed KA. Bioactive rearranged and halogenated semisynthetic derivatives of the marine natural product sarcophine. J Nat Prod. 2004 Dec;67(12):2017-23. PubMed PMID: 15620244.