WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461781

CAS#: 54692-41-0

Description: Saparal is an adaptogen of plant origin.

Chemical Structure

CAS# 54692-41-0

Theoretical Analysis

MedKoo Cat#: 461781
Name: Saparal
CAS#: 54692-41-0
Chemical Formula: C42H66O14
Exact Mass: 794.4453
Molecular Weight: 794.97
Elemental Analysis: C, 63.46; H, 8.37; O, 28.18

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
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Synonym: Saparal;

IUPAC/Chemical Name: (2S,3S,4S,5R)-6-(((3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-4,4,6a,6b,11,11,14b-heptamethyl-8a-((((3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)carbonyl)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid


InChi Code: InChI=1S/C42H66O14/c1-37(2)14-16-42(36(52)56-34-30(48)27(45)26(44)22(19-43)53-34)17-15-40(6)20(21(42)18-37)8-9-24-39(5)12-11-25(38(3,4)23(39)10-13-41(24,40)7)54-35-31(49)28(46)29(47)32(55-35)33(50)51/h8,21-32,34-35,43-49H,9-19H2,1-7H3,(H,50,51)/t21-,22-,23-,24+,25-,26-,27+,28-,29-,30-,31+,32-,34?,35?,39-,40+,41+,42-/m0/s1

SMILES Code: C[C@]12CC[C@H](OC3[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O3)C(C)(C)[C@@H]1CC[C@]4(C)[C@@H]2CC=C5[C@@]4(C)CC[C@]6(C(OC7[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O7)=O)[C@H]5CC(C)(C)CC6

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 794.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Paramonova MS, Gagarinova VM, Rodina MA, Guseva VM, Burmistrova VV, Osipova ZA, Aksenov OA. [The biological activity of saparal in an influenzal infection]. Vopr Virusol. 1994 May-Jun;39(3):131-4. Russian. PubMed PMID: 7522378.

2: Shikov AN, Pozharitskaya ON, Makarov VG. Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen: An overview of pharmacological studies. Phytomedicine. 2016 Nov 15;23(12):1409-1421. doi: 10.1016/j.phymed.2016.07.011. Epub 2016 Aug 3. Review. PubMed PMID: 27765361.

3: Azimov MI, Krakovskiĭ ME, Ashirmerov AKh. [The use of benzonal and saparal in the combined therapy of patients with acute inflammatory processes of the maxillofacial area]. Stomatologiia (Mosk). 1991 Sep-Oct;(5):47-9. Russian. PubMed PMID: 1798994.

4: Maksimova TV, Drozdov VA, Loshkarev PM, Kreshkov AP. [Analysis of sarracine bitartrate, gindarin, solasodine citrate and "Saparal" tablets by titration in nonaqueous media]. Farmatsiia. 1974 Nov-Dec;(6):51-3. Russian. PubMed PMID: 4464122.

5: Tsimmerman IaS, Golovanova ES, Romanova ZhN. [Clinico-immunologic evaluation of saparal in the treatment of recurrent ulcers]. Klin Med (Mosk). 1988 Jul;66(7):78-82. Russian. PubMed PMID: 3184834.

6: Tsimmerman IaS, Golovanova ES, Romanova ZhN. [Comparative effectiveness of decaris and saparal in recurrent peptic ulcer]. Sov Med. 1989;(10):88-91. Russian. PubMed PMID: 2694385.

7: Mal'chukovskiĭ LB, Libizov NI. [Determination of triterpene saponins in saparal powder and tablets]. Farmatsiia. 1971 Mar-Apr;20(2):68-71. Russian. PubMed PMID: 5562921.

8: Degtiareva TD, Katsnel'son BA, Pirvalova LI, Beresneva OIu, Gurvich VB, Kuz'min SV, Malykh OL. [Use of biologically active substances in preventing the toxic action of some heavy metals]. Gig Sanit. 2001 Sep-Oct;(5):71-3. Russian. PubMed PMID: 11665533.

9: Vasilenko IuK, Lisevitskaia LI, Frolova LM, Parfent'eva EP, Skul'te IV. [Hypolipidemic properties of triterpenoids]. Farmakol Toksikol. 1982 Sep-Oct;45(5):66-70. Russian. PubMed PMID: 7140959.

10: Vereshchagin IA, Koliagina NT, Bobrovitskaia AI. [Immunity in children having had viral hepatitis A and been treated with various immunomodulators in the acute period]. Vrach Delo. 1989 Mar;(3):118-20. Russian. PubMed PMID: 2750107.

11: Tsimmerman IaS, Babushkina GD. [Chronic noncalculous cholecystitis with refractory relapsing course (clinico-laboratory correlates)]. Ter Arkh. 1984;56(8):112-6. Russian. PubMed PMID: 6495190.