WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461775

CAS#: 96489-71-3

Description: Pyridaben is a pyridazinone derivative, is a new acaricide and insecticide for control of mites and some insects such as white flies, aphids and thrips. It acts as a complex I inhibitor.

Chemical Structure

CAS# 96489-71-3

Theoretical Analysis

MedKoo Cat#: 461775
Name: Pyridaben
CAS#: 96489-71-3
Chemical Formula: C19H25ClN2OS
Exact Mass: 364.1376
Molecular Weight: 364.93
Elemental Analysis: C, 62.53; H, 6.91; Cl, 9.71; N, 7.68; O, 4.38; S, 8.79

Price and Availability

Size Price Availability Quantity
25.0mg USD 210.0 2 Weeks
Bulk inquiry

Synonym: Pyridaben; Sanmite;

IUPAC/Chemical Name: 2-(tert-butyl)-5-((4-(tert-butyl)benzyl)thio)-4-chloropyridazin-3(2H)-one


InChi Code: InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3

SMILES Code: O=C1C(Cl)=C(SCC2=CC=C(C(C)(C)C)C=C2)C=NN1C(C)(C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 364.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Liu C, Lu D, Wang Y, Huang J, Wan K, Wang F. Residue and risk assessment of pyridaben in cabbage. Food Chem. 2014 Apr 15;149:233-6. doi: 10.1016/j.foodchem.2013.10.085. Epub 2013 Oct 30. PubMed PMID: 24295701.

2: Sugimoto N, Osakabe M. Cross-resistance between cyenopyrafen and pyridaben in the twospotted spider mite Tetranychus urticae (Acari: Tetranychidae). Pest Manag Sci. 2014 Jul;70(7):1090-6. doi: 10.1002/ps.3652. Epub 2013 Oct 13. PubMed PMID: 24030907.

3: Mou T, Zhao Z, Zhang P, Fang W, Peng C, Lu J, Wang Q, Ma Y, Zhang X. Synthesis and Bio-Evaluation of New (18) F-Labeled Pyridaben Analogs with Improved Stability for Myocardial Perfusion Imaging in Mice. Chem Biol Drug Des. 2015 Sep;86(3):351-61. doi: 10.1111/cbdd.12499. Epub 2015 Jan 12. PubMed PMID: 25529021.

4: Ebadi Manas G, Hasanzadeh S, Najafi G, Parivar K, Yaghmaei P. The effects of pyridaben pesticide on the DNA integrity of sperms and early in vitro embryonic development in mice. Iran J Reprod Med. 2013 Aug;11(8):605-10. PubMed PMID: 24639796; PubMed Central PMCID: PMC3941369.

5: Dong J, Qiu L, Ma Y, Wang C, Ju X. [Treatment for toxic encephalopathy caused by compound preparation of avermectins and pyridaben]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2015 Jan;33(1):57. Chinese. PubMed PMID: 25876980.

6: Sun D, Zhu Y, Pang J, Zhou Z, Jiao B. Residue level, persistence and safety of spirodiclofen-pyridaben mixture in citrus fruits. Food Chem. 2016 Mar 1;194:805-10. doi: 10.1016/j.foodchem.2015.08.044. Epub 2015 Aug 14. PubMed PMID: 26471621.

7: Li S, Xu M, Wu X, Luo J. Synergetic recognition and separation of kelthane and pyridaben base on magnetic molecularly imprinted polymer nanospheres. J Sep Sci. 2016 Oct;39(20):4019-4026. doi: 10.1002/jssc.201600699. Epub 2016 Oct 6. PubMed PMID: 27550709.

8: Charli A, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Alterations in mitochondrial dynamics induced by tebufenpyrad and pyridaben in a dopaminergic neuronal cell culture model. Neurotoxicology. 2016 Mar;53:302-313. doi: 10.1016/j.neuro.2015.06.007. Epub 2015 Jul 2. PubMed PMID: 26141520; PubMed Central PMCID: PMC4698251.

9: Kim SW, Abd El-Aty AM, Rahman MM, Choi JH, Choi OJ, Rhee GS, Chang MI, Kim H, Abid MD, Shin SC, Shim JH. Detection of pyridaben residue levels in hot pepper fruit and leaves by liquid chromatography-tandem mass spectrometry: effect of household processes. Biomed Chromatogr. 2015 Jul;29(7):990-7. doi: 10.1002/bmc.3383. Epub 2014 Nov 17. PubMed PMID: 25402259.

10: Zhang C, Zhao H, Wu M, Hu X, Cai X, Ping L, Li Z. Simultaneous determination of procymidone, pyridaben and beta-cypermethrin residues in tea solution by GC-ECD. J Chromatogr Sci. 2012 Nov-Dec;50(10):940-4. doi: 10.1093/chromsci/bms094. Epub 2012 Jun 11. PubMed PMID: 22689906.

11: Ebadi Manas G, Hasanzadeh S, Parivar K. The effects of pyridaben pesticide on the histomorphometric, hormonal alternations and reproductive functions of BALB/c mice. Iran J Basic Med Sci. 2013 Oct;16(10):1055-64. PubMed PMID: 24379962; PubMed Central PMCID: PMC3874091.

12: Mou T, Zhao Z, You L, Li Y, Wang Q, Fang W, Lu J, Peng C, Zhang X. Synthesis and Evaluation of (18)F-labeled Pyridaben Analogues for Myocardial Perfusion Imaging in Mice, Rats and Chinese mini-swine. Sci Rep. 2016 Sep 20;6:33450. doi: 10.1038/srep33450. PubMed PMID: 27646847; PubMed Central PMCID: PMC5028837.

13: Kim YJ, Park HM, Cho JR, Ahn YJ. Multiple resistance and biochemical mechanisms of pyridaben resistance in Tetranychus urticae (Acari: Tetranychidae). J Econ Entomol. 2006 Jun;99(3):954-8. PubMed PMID: 16813336.

14: Mou T, Zhao Z, Fang W, Peng C, Guo F, Liu B, Ma Y, Zhang X. Synthesis and preliminary evaluation of 18F-labeled pyridaben analogues for myocardial perfusion imaging with PET. J Nucl Med. 2012 Mar;53(3):472-9. doi: 10.2967/jnumed.111.088096. Epub 2012 Feb 2. PubMed PMID: 22302832.

15: Park JJ, Kim M, Lee JH, Shin KI, Lee SE, Kim JG, Cho K. Sublethal effects of fenpyroximate and pyridaben on two predatory mite species, Neoseiulus womersleyi and Phytoseiulus persimilis (Acari, Phytoseiidae). Exp Appl Acarol. 2011 Jul;54(3):243-59. doi: 10.1007/s10493-011-9435-7. Epub 2011 Feb 27. PubMed PMID: 21359626.

16: Navarro A, Bández MJ, Gómez C, Repetto MG, Boveris A. Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity. J Bioenerg Biomembr. 2010 Oct;42(5):405-12. doi: 10.1007/s10863-010-9309-4. Epub 2010 Oct 1. PubMed PMID: 20886364.

17: Suh E, Koh SH, Lee JH, Shin KI, Cho K. Evaluation of resistance pattern to fenpyroximate and pyridaben in Tetranychus urticae collected from greenhouses and apple orchards using lethal concentration-slope relationship. Exp Appl Acarol. 2006;38(2-3):151-65. PubMed PMID: 16596349.

18: Boulaid M, Aguilera A, Busonera V, Camacho F, Monterreal AV, Valverde A. Assessing supercritical fluid extraction for the analysis of fipronil, kresoxim-methyl, acrinathrin, and pyridaben residues in melon. J Environ Sci Health B. 2007 Sep-Oct;42(7):809-15. PubMed PMID: 17763038.

19: Valverde A, Aguilera A, Rodríguez M, Boulaid M, Soussi-El Begrani M. Pesticide residue levels in peppers grown in a greenhouse after multiple applications of pyridaben and tralomethrin. J Agric Food Chem. 2002 Dec 4;50(25):7303-7. PubMed PMID: 12452649.

20: Rand GM, Clark JR, Holmes CM. The use of outdoor freshwater pond microcosms. III. Responses of phytoplankton and periphyton to pyridaben. Environ Toxicol. 2001;16(1):96-103. PubMed PMID: 11345551.