WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 461773
Description: Sanguiin h 11 is a compound purified from the plant Sanguisorba officinalis and has proven to be a potent inhibitor of chemoattractant-dependent and independent neutrophil movement.
MedKoo Cat#: 461773
Name: Sanguiin h 11
Chemical Formula: C41H28O26
Exact Mass: 936.0869
Molecular Weight: 936.64
Elemental Analysis: C, 52.58; H, 3.01; O, 44.41
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Sanguiin h 11; Sanguiin H-11;
IUPAC/Chemical Name: (6aR,7S,8aR,21aR,21bS)-1,2,3,13,14,15,16,17,18,25,26,27-dodecahydroxy-5,11,20,23-tetraoxo-5,6a,7,8a,9,11,20,21a,21b,23-decahydrodibenzo[g,i]dibenzo[6',7':8',9'][1,4]dioxecino[2',3':4,5]pyrano[3,2-b][1,5]dioxacycloundecin-7-yl 3,4,5-trihydroxybenzoate
InChi Key: SWRFKGRMQVLMKA-JIZJWZDPSA-N
InChi Code: InChI=1S/C41H28O26/c42-13-1-8(2-14(43)24(13)48)36(57)67-41-35-34(65-39(60)11-5-17(46)27(51)31(55)22(11)23-12(40(61)66-35)6-18(47)28(52)32(23)56)33-19(63-41)7-62-37(58)9-3-15(44)25(49)29(53)20(9)21-10(38(59)64-33)4-16(45)26(50)30(21)54/h1-6,19,33-35,41-56H,7H2/t19-,33-,34+,35-,41+/m1/s1
SMILES Code: O=C(O[C@H](O1)[C@@](OC(C2=CC(O)=C(O)C(O)=C2C3=C(O)C(O)=C(O)C=C34)=O)([H])[C@@]([C@]([C@@]1([H])COC(C5=CC(O)=C(O)C(O)=C5C6=C(O)C(O)=C(O)C=C67)=O)([H])OC7=O)([H])OC4=O)C8=CC(O)=C(O)C(O)=C8
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 936.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Konishi K, Urada M, Adachi I, Tanaka T. Inhibitory effect of sanguiin H-11 on chemotaxis of neutrophil. Biol Pharm Bull. 2000 Feb;23(2):213-8. PubMed PMID: 10706387.
2: Yokozawa T, Chen CP, Tanaka T, Kitani K. A study on the nitric oxide production-suppressing activity of sanguisorbae radix components. Biol Pharm Bull. 2000 Jun;23(6):717-22. PubMed PMID: 10864022.