Sulfathiourea

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461733

CAS#: 515-49-1

Description: Sulfathiourea is a sulfonamide antibacterial.

Chemical Structure

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Sulfathiourea
CAS# 515-49-1
Instruction

Theoretical Analysis

MedKoo Cat#: 461733
Name: Sulfathiourea
CAS#: 515-49-1
Chemical Formula: C7H9N3O2S2
Exact Mass: 231.01
Molecular Weight: 231.280
Elemental Analysis: C, 36.35; H, 3.92; N, 18.17; O, 13.83; S, 27.72

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Sulfathiourea; Fontamide; Badional; Salvoseptyl; Sulfathiocarbamidum;

IUPAC/Chemical Name: 4-amino-N-carbamothioylbenzenesulfonamide

InChi Key: UEMLYRZWLVXWRU-UHFFFAOYSA-N

InChi Code: InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)

SMILES Code: S=C(N)NS(=O)(C1=CC=C(N)C=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 231.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: El-Fatatry HM, Sharaf El-Deen MM, Amer MM. Application of Henderson equation for the determination of weakly acidic pharmaceutical compounds. Part 1: Determination of sulfathiourea. Pharmazie. 1978 May;33(5):282-4. PubMed PMID: 674338.

2: Czeizel AE, Puhó E, Sørensen HT, Olsen J. Possible association between different congenital abnormalities and use of different sulfonamides during pregnancy. Congenit Anom (Kyoto). 2004 Jun;44(2):79-86. PubMed PMID: 15198720.

3: THIERS H, COLOMB D, FAYOLLE J. [Sulfathiourea in therapy of nodular or patchy eruptive hypodermatites]. Bull Soc Fr Dermatol Syphiligr. 1957 Apr-May;64(2):140-1. French. PubMed PMID: 13460623.

4: SCHOOG M. [Sulfathiourea, chemistry, pharmacology and clinical aspects]. Z Haut Geschlechtskr. 1953 Nov 15;15(10):315-8. Undetermined Language. PubMed PMID: 13137202.

5: SAMPAIO S, MARTIRANI A. [Treatment of veneral chancre with sulfathiourea]. Rev Paul Med. 1949 Sep;35(3):207-10. Portuguese. PubMed PMID: 18139882.

6: ZOLLNER E, VASTAGH G. [Colorimetric determination of sulfathiourea (badional)]. Pharm Zentralhalle Dtschl. 1958 May;97(5):219-23. German. PubMed PMID: 13566968.

7: WEINSTEIN L, CHANG TW, MURPHY EB, HUDSON JB. Studies of sulfathiourea; in vivo and in vitro activity, reactivity to p-aminobenzoic acid, mode of action, with some comparisons with sulfadimetine. Antibiot Chemother (Northfield). 1956 Jul;6(7):429-43. PubMed PMID: 24544024.

8: Palló N, Török I, Paál T. [Chromatographic separation and simultaneous determination of sulfathiourea, sulfamethoxypyridazine and sulfadimidine]. Acta Pharm Hung. 1988 May;58(3):105-13. Hungarian. PubMed PMID: 3245446.

9: THIERS H, COLOMB. [The syndrome of focal angina, rheumatismal state and so-called allergic hypodermitis; treatment by sulfathiourea]. Rev Rhum Mal Osteoartic. 1953 Aug-Sep;20(8-9):645-7. Undetermined Language. PubMed PMID: 13121788.

10: ROCHE G, PELLERIN F, JUTEAU C, JUTEAU J. [Comparative pleural permeability of healthy and pathological pleura; injections of sulfathiourea]. Rev Tuberc. 1957 Jul-Aug;21(7-8):833-56. French. PubMed PMID: 13495112.

11: BERGMANN F. Suflathiourea. J Am Chem Soc. 1946 May;68:761-4. PubMed PMID: 21024878.

12: Hong YL, Hossler PA, Calhoun DH, Meshnick SR. Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrob Agents Chemother. 1995 Aug;39(8):1756-63. PubMed PMID: 7486915; PubMed Central PMCID: PMC162822.

13: CELICE J, BOUDREAUX J. [Not Available]. Gaz Med Fr. 1946;53(6):133-7. Undetermined Language. PubMed PMID: 21025532.

14: Askal HF, Saleh GA. Spectrophotometric methods for the determination of sulphathiourea. J Pharm Biomed Anal. 1991;9(4):297-301. PubMed PMID: 1911981.

15: Abdellatef HE, Elbalkiny MN, Aboulkheir A. Determination of sulphacetamide, sulphadimidine or sulphathiourea in the presence of their degradation products using first derivative spectrophotometry. J Pharm Biomed Anal. 1989;7(5):571-6. PubMed PMID: 2490761.