WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461716

CAS#: 6882-07-1

Description: Salicifoline is a water-soluble quaternary ammonium alkaloid.

Chemical Structure

CAS# 6882-07-1

Theoretical Analysis

MedKoo Cat#: 461716
Name: Salicifoline
CAS#: 6882-07-1
Chemical Formula: C12H20NO2
Exact Mass: 210.15
Molecular Weight: 210.290
Elemental Analysis: C, 68.54; H, 9.59; N, 6.66; O, 15.22

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Salicifoline;

IUPAC/Chemical Name: 2-(3-hydroxy-4-methoxyphenyl)-N,N,N-trimethylethan-1-aminium


InChi Code: InChI=1S/C12H19NO2/c1-13(2,3)8-7-10-5-6-12(15-4)11(14)9-10/h5-6,9H,7-8H2,1-4H3/p+1

SMILES Code: C[N+](C)(C)CCC1=CC=C(OC)C(O)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 210.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Efdi M, Itoh T, Akao Y, Nozawa Y, Koketsu M, Ishihara H. The isolation of
secondary metabolites and in vitro potent anti-cancer activity of clerodermic
acid from Enicosanthum membranifolium. Bioorg Med Chem. 2007 Jun
1;15(11):3667-71. Epub 2007 Mar 18. PubMed PMID: 17400462.

2: Song WZ, Cui JF, Zhang GD. [Studies on the medicinal plants of Magnoliaceae
tu-hou-po of Manglietia]. Yao Xue Xue Bao. 1989;24(4):295-9. Chinese. PubMed
PMID: 2530753.

3: Okumura W, Aoki D, Matsushita Y, Yoshida M, Fukushima K. Distribution of
salicifoline in freeze-fixed stems of Magnolia kobus as observed by
cryo-TOF-SIMS. Sci Rep. 2017 Jul 19;7(1):5939. doi: 10.1038/s41598-017-06444-0.
PubMed PMID: 28725003; PubMed Central PMCID: PMC5517595.

4: Cui JF, Zhang GD, Song WZ. [Reversed phase ion-pair HPLC determination of
quaternary ammonium alkaloids in the traditional Chinese drug hou-po (Magnolia
officinalis)]. Yao Xue Xue Bao. 1988 May;23(5):383-7. Chinese. PubMed PMID: