WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 461692
Description: Sadopine is an excellent high affinity, high specific activity radioligand to label selectively the DHP receptor of L-type Ca2+ channels in tissue sections as well as in membrane fragments.
MedKoo Cat#: 461692
Chemical Formula: C30H40F3N3O7S
Exact Mass: 643.2539
Molecular Weight: 643.71
Elemental Analysis: C, 55.98; H, 6.26; F, 8.85; N, 6.53; O, 17.40; S, 4.98
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
IUPAC/Chemical Name: 3-(2-(2-((tert-butoxycarbonyl)amino)-4-(methylthio)butanamido)ethyl) 5-ethyl 2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChi Key: IAGRRCQYHMPXJH-UHFFFAOYSA-N
InChi Code: InChI=1S/C30H40F3N3O7S/c1-8-41-26(38)22-17(2)35-18(3)23(24(22)19-11-9-10-12-20(19)30(31,32)33)27(39)42-15-14-34-25(37)21(13-16-44-7)36-28(40)43-29(4,5)6/h9-12,21,24,35H,8,13-16H2,1-7H3,(H,34,37)(H,36,40)
SMILES Code: O=C(C1=C(C)NC(C)=C(C(OCC)=O)C1C2=CC=CC=C2C(F)(F)F)OCCNC(C(NC(OC(C)(C)C)=O)CCSC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 643.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Knaus HG, Striessnig J, Hering S, Marrer S, Schwenner E, Höltje HD, Glossmann H. [35S]sadopine, a novel high affinity, high specific activity, L-type Ca2+ channel probe: characterization of two equipotent diastereomers with opposite allosteric properties. Mol Pharmacol. 1992 Feb;41(2):298-307. PubMed PMID: 1311409.
2: Glossmann H, Striessnig J, Knaus HG, Müller J, Grassegger A, Höltje HD, Marrer S, Hymel L, Schindler HG. Structure of calcium channels. Ann N Y Acad Sci. 1989;560:198-214. Review. PubMed PMID: 2545133.