WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 461662
Description: S 9795 is a methylxanthine derivative and acts as a potent inhibitor of bronchoconstriction in vivo.
MedKoo Cat#: 461662
Name: S 9795
Chemical Formula: C29H36N6O2
Exact Mass: 500.29
Molecular Weight: 500.64
Elemental Analysis: C, 69.57; H, 7.25; N, 16.79; O, 6.39
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: S 9795; S-9795; S9795;
IUPAC/Chemical Name: 8-(4-benzhydryl-2-ethylpiperazin-1-yl)-3-isobutyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione
InChi Key: RLIITPBGWVXBBZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C29H36N6O2/c1-5-23-19-33(25(21-12-8-6-9-13-21)22-14-10-7-11-15-22)16-17-34(23)28-30-24-26(31-28)35(18-20(2)3)29(37)32(4)27(24)36/h6-15,20,23,25H,5,16-19H2,1-4H3,(H,30,31)
SMILES Code: O=C(N1C)N(CC(C)C)C2=C(NC(N3C(CC)CN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3)=N2)C1=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 500.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Bianchi G, Caccia S, Della Vedova F, Garattini S. Kinetics and brain uptake of S 9795, a new xanthine derivate, in rats. Eur J Drug Metab Pharmacokinet. 1989 Jul-Sep;14(3):201-8. PubMed PMID: 2612517.
2: Lejeune P, Naeije R. Effects of progressively increased doses of theophylline and of S 9795 on hemodynamics, blood gases and lung mechanics in dogs. Arch Int Pharmacodyn Ther. 1988 Jul-Aug;294:215-27. PubMed PMID: 3233049.
3: Busk MF, Flavahan NA, Vanhoutte PM. Effects of the methyl xanthine S 9795 on isolated bronchi of the dog. J Pharmacol Exp Ther. 1990 Sep;254(3):1045-53. PubMed PMID: 2395105.
4: Lejeune P, Leeman M, Mélot C, Naeije R. Effects of theophylline and S 9795 on hyperoxic and hypoxic pulmonary vascular tone in intact dogs. Eur Respir J. 1989 Apr;2(4):370-6. PubMed PMID: 2737274.
5: Duhault J, Boulanger M, Lonchampt M, Tisserand F, Holstorp S, Saint-Romas G, Pennel L, Regnier G. Pharmacological properties of a new antiasthmatic xanthine derivative devoid of central stimulatory activity. Arzneimittelforschung. 1987 Dec;37(12):1353-62. PubMed PMID: 2835053.
6: Devreux V, Plasman PO, Lebrun P, Herchuelz A. Effect of a new xanthine derivative on the release of insulin from rat pancreatic islets. Arzneimittelforschung. 1990 Mar;40(3):268-71. PubMed PMID: 2189420.