Neurodazine
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MedKoo CAT#: 563655

CAS#: 937807-66-4

Description: Neurodazine is a neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons.


Price and Availability

Size Price Shipping out time Quantity
5mg USD 280 2 Weeks
10mg USD 420 2 Weeks
25mg USD 730 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

Neurodazine, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 563655
Name: Neurodazine
CAS#: 937807-66-4
Chemical Formula: C27H21ClN2O3
Exact Mass: 456.1241
Molecular Weight: 456.92
Elemental Analysis: C, 70.97; H, 4.63; Cl, 7.76; N, 6.13; O, 10.50


Synonym: Neurodazine;

IUPAC/Chemical Name: 2-[5-(3-Chloro-phenyl)-furan-2-yl]-4,5-bis-(4-methoxy-phenyl)-1H-imidazole

InChi Key: FEEOFPAEDSMOTO-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)

SMILES Code: COC1=CC=C(C2=C(C3=CC=C(OC)C=C3)N=C(C4=CC=C(C5=CC=CC(Cl)=C5)O4)N2)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Halder D, Kim GH, Shin I. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11(10):2727-37. doi: 10.1039/c5mb00161g. PubMed PMID: 25872738.

2: Pérez-Caaveiro C, Pérez Sestelo J, Martínez MM, Sarandeses LA. Triorganoindium reagents in selective palladium-catalyzed cross-coupling with iodoimidazoles: synthesis of neurodazine. J Org Chem. 2014 Oct 17;79(20):9586-93. doi: 10.1021/jo501664p. Epub 2014 Oct 1. PubMed PMID: 25203769.

3: Kim GH, Halder D, Park J, Namkung W, Shin I. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4. doi: 10.1002/anie.201404871. Epub 2014 Jul 9. PubMed PMID: 25044422.