Uniconazole-P

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 599171

CAS#: 83657-17-4

Description: Uniconazole-P is a bioactive agricultural chemical.


Chemical Structure

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Uniconazole-P
CAS# 83657-17-4

Theoretical Analysis

MedKoo Cat#: 599171
Name: Uniconazole-P
CAS#: 83657-17-4
Chemical Formula: C15H18ClN3O
Exact Mass: 291.11
Molecular Weight: 291.770
Elemental Analysis: C, 61.75; H, 6.22; Cl, 12.15; N, 14.40; O, 5.48

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Uniconazole-P; S-3307D; S 3307D; S3307D; Uniconazole P; Lomica; (S)-S3307;

IUPAC/Chemical Name: (S,E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol

InChi Key: YNWVFADWVLCOPU-MAUPQMMJSA-N

InChi Code: InChI=1S/C15H18ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-10,14,20H,1-3H3/b13-8+/t14-/m1/s1

SMILES Code: O[C@@H](C(C)(C)C)/C(N1N=CN=C1)=C\C2=CC=C(Cl)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 291.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Miyazaki S, Katsumata T, Natsume M, Kawaide H. The CYP701B1 of Physcomitrella patens is an ent-kaurene oxidase that resists inhibition by uniconazole-P. FEBS Lett. 2011 Jun 23;585(12):1879-83. doi: 10.1016/j.febslet.2011.04.057. Epub 2011 Apr 30. PubMed PMID: 21545802.

2: Kojima K, Goto A, Nakashima S. Effects of Uniconazole-P on Abscission and Endogenous ABA, IAA, and GA-like Substances Levels of Satsuma Mandarin Fruitlet. Biosci Biotechnol Biochem. 1996 Jan;60(5):901-2. doi: 10.1271/bbb.60.901. PubMed PMID: 27281152.

3: Kodaka R, Sugano T, Katagi T. Metabolism of uniconazole-P in water-sediment systems under illumination. Environ Toxicol Chem. 2006 Feb;25(2):310-6. PubMed PMID: 16519290.

4: Jiang S, Honma T, Nakamura T, Furukawa I, Yamamoto F. Regulation by uniconazole-P and gibberellins of morphological and anatomical responses of Fraxinus mandshurica seedlings to gravity. IAWA J. 1998;19(3):311-20. PubMed PMID: 11542470.

5: Saito S, Okamoto M, Shinoda S, Kushiro T, Koshiba T, Kamiya Y, Hirai N, Todoroki Y, Sakata K, Nambara E, Mizutani M. A plant growth retardant, uniconazole, is a potent inhibitor of ABA catabolism in Arabidopsis. Biosci Biotechnol Biochem. 2006 Jul;70(7):1731-9. Epub 2006 Jul 1. PubMed PMID: 16819156.

6: Jiang S, Xu K, Wang YZ, Ren YP, Gu S. Role of GA3, GA4 and uniconazole-P in controlling gravitropism and tension wood formation in Fraxinus mandshurica Rupr. var. japonica Maxim. seedlings. J Integr Plant Biol. 2008 Jan;50(1):19-28. doi: 10.1111/j.1744-7909.2007.00552.x. PubMed PMID: 18666948.

7: Nugroho WD, Yamagishi Y, Nakaba S, Fukuhara S, Begum S, Marsoem SN, Ko JH, Jin HO, Funada R. Gibberellin is required for the formation of tension wood and stem gravitropism in Acacia mangium seedlings. Ann Bot. 2012 Sep;110(4):887-95. doi: 10.1093/aob/mcs148. Epub 2012 Jul 26. PubMed PMID: 22843341; PubMed Central PMCID: PMC3423806.

8: Nugroho WD, Nakaba S, Yamagishi Y, Begum S, Marsoem SN, Ko JH, Jin HO, Funada R. Gibberellin mediates the development of gelatinous fibres in the tension wood of inclined Acacia mangium seedlings. Ann Bot. 2013 Nov;112(7):1321-9. doi: 10.1093/aob/mct198. Epub 2013 Sep 15. PubMed PMID: 24043495; PubMed Central PMCID: PMC3806530.

9: Wagatsuma T, Khan MS, Watanabe T, Maejima E, Sekimoto H, Yokota T, Nakano T, Toyomasu T, Tawaraya K, Koyama H, Uemura M, Ishikawa S, Ikka T, Ishikawa A, Kawamura T, Murakami S, Ueki N, Umetsu A, Kannari T. Higher sterol content regulated by CYP51 with concomitant lower phospholipid content in membranes is a common strategy for aluminium tolerance in several plant species. J Exp Bot. 2015 Feb;66(3):907-18. doi: 10.1093/jxb/eru455. Epub 2014 Nov 21. PubMed PMID: 25416794; PubMed Central PMCID: PMC4321553.

10: Inada S, Shimmen T. Regulation of elongation growth by gibberellin in root segments of Lemna minor. Plant Cell Physiol. 2000 Aug;41(8):932-9. PubMed PMID: 11038053.

11: Rademacher W. GROWTH RETARDANTS: Effects on Gibberellin Biosynthesis and Other Metabolic Pathways. Annu Rev Plant Physiol Plant Mol Biol. 2000 Jun;51:501-531. PubMed PMID: 15012200.

12: Motonami N, Ueno K, Nakashima H, Nomura S, Mizutani M, Takikawa H, Sugimoto Y. The bioconversion of 5-deoxystrigol to sorgomol by the sorghum, Sorghum bicolor (L.) Moench. Phytochemistry. 2013 Sep;93:41-8. doi: 10.1016/j.phytochem.2013.02.017. Epub 2013 Apr 15. PubMed PMID: 23597492.

13: Inada S, Shimmen T. Involvement of cortical microtubules in plastic extension regulated by gibberellin in Lemna minor root. Plant Cell Physiol. 2001 Apr;42(4):395-403. PubMed PMID: 11333310.

14: Okamoto M, Kushiro T, Jikumaru Y, Abrams SR, Kamiya Y, Seki M, Nambara E. ABA 9'-hydroxylation is catalyzed by CYP707A in Arabidopsis. Phytochemistry. 2011 Jun;72(8):717-22. doi: 10.1016/j.phytochem.2011.02.004. Epub 2011 Mar 15. PubMed PMID: 21414645.

15: Maekawa T, Maekawa-Yoshikawa M, Takeda N, Imaizumi-Anraku H, Murooka Y, Hayashi M. Gibberellin controls the nodulation signaling pathway in Lotus japonicus. Plant J. 2009 Apr;58(2):183-94. doi: 10.1111/j.1365-313X.2008.03774.x. Epub 2008 Dec 2. PubMed PMID: 19121107.

16: Inada S, Tominaga M, Shimmen T. Regulation of root growth by gibberellin in Lemna minor. Plant Cell Physiol. 2000 Jun;41(6):657-65. PubMed PMID: 10945334.

17: Kitahata N, Saito S, Miyazawa Y, Umezawa T, Shimada Y, Min YK, Mizutani M, Hirai N, Shinozaki K, Yoshida S, Asami T. Chemical regulation of abscisic acid catabolism in plants by cytochrome P450 inhibitors. Bioorg Med Chem. 2005 Jul 15;13(14):4491-8. PubMed PMID: 15882944.

18: Taneyama M, Okamoto T, Yamane H, Minamikawa T. Involvement of gibberellins in expression of a cysteine proteinase (SH-EP) in cotyledons of Vigna mungo seedlings. Plant Cell Physiol. 2001 Nov;42(11):1290-3. PubMed PMID: 11726715.

19: Furukawa K, Yang YY, Honda I, Yanagisawa T, Sakurai A, Takahashi N, Kamiya Y. Effects of Ethylene and Gibberellins on the Elongation of Rice Seedlings (Oryza sativa L.). Biosci Biotechnol Biochem. 1997 Jan;61(5):864-869. doi: 10.1271/bbb.61.864. PubMed PMID: 28862568.

20: Aoki T, Kitano H, Kameya N, Nakamura I. Accelerated shoot overgrowth of rice mutant ao-1 is epistatic to gibberellin-sensitive and -insensitive dwarf mutants. J Plant Res. 2002 Jun;115(3):195-202. PubMed PMID: 12579369.