QZM 00829 | CAS#2107273-62-9 | Fluorescent PEG Linker

QZM 00829
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 572301

CAS#: 2107273-62-9

Description: QZM 00829, also known as N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG derivative containing cyanine dye with excitation/emission maximum 555/570 nm and an alkyne group, which enables copper-catalyzed Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

QZM 00829

CAS# 2107273-62-9

Product data Instruction

Theoretical Analysis

MedKoo Cat#: 572301
Name: QZM 00829
CAS#: 2107273-62-9
Chemical Formula: C45H65ClN2O10
Exact Mass: 0.00
Molecular Weight: 829.470
Elemental Analysis: C, 65.16; H, 7.90; Cl, 4.27; N, 3.38; O, 19.29

Price and Availability

Size	Price	Availability	Quantity
1mg	USD 410
2mg	USD 640
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3; QZM 00829; QZM-00829; QZM00829

IUPAC/Chemical Name: 2-((E)-3-((E)-5-((2,5,8,11-tetraoxatridecan-13-yl)oxy)-1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)-5-((3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy)-1,3,3-trimethyl-3H-1l4-indole, chloride salt

InChi Key: QMLMWDKHWJAZGQ-ZPKNMNKASA-M

InChi Code: InChI=1S/C45H65N2O10.ClH/c1-9-17-49-20-21-51-24-25-53-27-29-55-31-33-57-37-14-16-41-39(35-37)45(4,5)43(47(41)7)12-10-11-42-44(2,3)38-34-36(13-15-40(38)46(42)6)56-32-30-54-28-26-52-23-22-50-19-18-48-8;/h1,10-16,34-35H,17-33H2,2-8H3;1H/p-1/b12-10+,42-11+;

SMILES Code: CC(C1=CC(OCCOCCOCCOCCOC)=CC=C1N/2C)(C)C2=C/C=C/C3=[N](C)C(C=CC(OCCOCCOCCOCCOCC#C)=C4)=C4C3(C)C.[Cl-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >3 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info: Solubility: Water, DMSO, DMF, DCM Excitation maximum (nm): 555 Extinction coefficient and excitation maximum, Lmol-1cm-1: 150000 Emission maximum (nm): 570

Product Data:

Product Data

Instruction:

View handling instruction

Biological target:	QZM 00829 is a PEG derivative containing cyanine dye with excitation/emission maximum 555/570 nm and an alkyne group, which enables copper-catalyzed Click Chemistry.
In vitro activity:	To be determined
In vivo activity:	To be determined

Preparing Stock Solutions

The following data is based on the product molecular weight 829.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:	To be determined
In vitro protocol:	To be determined
In vivo protocol:	To be determined

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Chen X, Zhang X, Wang HY, Chen Z, Wu FG. Subcellular Fate of a Fluorescent Cholesterol-Poly(ethylene glycol) Conjugate: An Excellent Plasma Membrane Imaging Reagent. Langmuir. 2016 Oct 4;32(39):10126-10135. Epub 2016 Sep 21. PubMed PMID: 27597442.

2: Chen G, Wang L, Cordie T, Vokoun C, Eliceiri KW, Gong S. Multi-functional self-fluorescent unimolecular micelles for tumor-targeted drug delivery and bioimaging. Biomaterials. 2015 Apr;47:41-50. doi: 10.1016/j.biomaterials.2015.01.006. Epub 2015 Feb 4. PubMed PMID: 25682159; PubMed Central PMCID: PMC4329508.

3: Ruan S, Qian J, Shen S, Chen J, Zhu J, Jiang X, He Q, Yang W, Gao H. Fluorescent carbonaceous nanodots for noninvasive glioma imaging after angiopep-2 decoration. Bioconjug Chem. 2014 Dec 17;25(12):2252-9. doi: 10.1021/bc500474p. Epub 2014 Nov 11. PubMed PMID: 25387274.

4: Ruan S, Wan J, Fu Y, Han K, Li X, Chen J, Zhang Q, Shen S, He Q, Gao H. PEGylated fluorescent carbon nanoparticles for noninvasive heart imaging. Bioconjug Chem. 2014 Jun 18;25(6):1061-8. doi: 10.1021/bc5001627. Epub 2014 May 22. PubMed PMID: 24852402.

5: Paira TK, Saha A, Banerjee S, Das T, Das P, Jana NR, Mandal TK. Fluorescent amphiphilic PEG-peptide-PEG triblock conjugate micelles for cell imaging. Macromol Biosci. 2014 Jul;14(7):929-35. doi: 10.1002/mabi.201400083. Epub 2014 Mar 31. PubMed PMID: 24687698.

6: Okuda T, Kobayashi Y, Yanamoto S, Okamoto H. PEG conjugation of a near-infrared fluorescent probe for noninvasive dual imaging of lung deposition and gene expression by pulmonary gene delivery. J Drug Target. 2012 Nov;20(9):801-12. doi: 10.3109/1061186X.2012.722639. Epub 2012 Sep 26. PubMed PMID: 23009266.

Your view history

QZM 00829 featured