UK-78282 HCl
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MedKoo CAT#: 563615

CAS#: 136647-02-4 (HCl)

Description: UK-78282 HCl is a blocker of the KV1.3 and KV1.4 voltage-gated potassium channels.


Price and Availability

Size Price Shipping out time Quantity
10mg USD 425 2 Weeks
50mg USD 1650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-30. Prices are subject to change without notice.

UK-78282 HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 563615
Name: UK-78282 HCl
CAS#: 136647-02-4 (HCl)
Chemical Formula: C29H36ClNO2
Exact Mass: 465.2435
Molecular Weight: 466.06
Elemental Analysis: C, 74.74; H, 7.79; Cl, 7.61; N, 3.01; O, 6.87


Related CAS #: 191217-42-2 (free base)   136647-02-4 (HCl)    

Synonym: UK-78282 Hydrochloride; UK 78282 Hydrochloride; UK78282 Hydrochloride; UK-78282 HCl; UK 78282 HCl; UK78282 HCl;

IUPAC/Chemical Name: 4-(Benzhydryloxymethyl)-1-[3-(4-methoxyphenyl)propyl]piperidine hydrochloride

InChi Key: ZZSQARULZYQMIG-UHFFFAOYSA-N

InChi Code: InChI=1S/C29H35NO2.ClH/c1-31-28-16-14-24(15-17-28)9-8-20-30-21-18-25(19-22-30)23-32-29(26-10-4-2-5-11-26)27-12-6-3-7-13-27;/h2-7,10-17,25,29H,8-9,18-23H2,1H3;1H

SMILES Code: COC1=CC=C(CCCN2CCC(COC(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C=C1.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Hanson DC, Nguyen A, Mather RJ, Rauer H, Koch K, Burgess LE, Rizzi JP, Donovan CB, Bruns MJ, Canniff PC, Cunningham AC, Verdries KA, Mena E, Kath JC, Gutman GA, Cahalan MD, Grissmer S, Chandy KG. UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation. Br J Pharmacol. 1999 Apr;126(8):1707-16. PubMed PMID: 10372812; PubMed Central PMCID: PMC1565958.