Aldicarb sulfone
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MedKoo CAT#: 471003

CAS#: 1646-88-4

Description: Aldicarb sulfone is a metabolite and degradation product of the carbamate pesticide aldicarb, the active ingredient in the insecticide TEMIK, which was introduced to the agricultural community over 25 years ago. It has been registered worldwide to control a wide variety of insect, mite, and nematode pests in agriculture.


Chemical Structure

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Aldicarb sulfone
CAS# 1646-88-4

Theoretical Analysis

MedKoo Cat#: 471003
Name: Aldicarb sulfone
CAS#: 1646-88-4
Chemical Formula: C7H14N2O4S
Exact Mass: 222.07
Molecular Weight: 222.259
Elemental Analysis: C, 37.83; H, 6.35; N, 12.60; O, 28.79; S, 14.42

Price and Availability

Size Price Availability Quantity
100mg USD 300
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Synonym: Aldicarb sulfone

IUPAC/Chemical Name: (E)-2-methyl-2-(methylsulfonyl)propanal O-methylcarbamoyl oxime

InChi Key: YRRKLBAKDXSTNC-WEVVVXLNSA-N

InChi Code: InChI=1S/C7H14N2O4S/c1-7(2,14(4,11)12)5-9-13-6(10)8-3/h5H,1-4H3,(H,8,10)/b9-5+

SMILES Code: CNC(O/N=C/C(C)(C)S(C)(=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 222.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Ding K, Xu W, Li K, Guo L, Sun J. [Dynamic behavior of aldicarb and its metabolites in cabbage by liquid chromatography-tandem mass spectrometry]. Se Pu. 2016 Feb;34(2):165-9. Chinese. PubMed PMID: 27382721.

2: de Siqueira A, Salvagni FA, Yoshida AS, Gonçalves-Junior V, Calefi AS, Fukushima AR, Spinosa Hde S, Maiorka PC. Poisoning of cats and dogs by the carbamate pesticides aldicarb and carbofuran. Res Vet Sci. 2015 Oct;102:142-9. doi: 10.1016/j.rvsc.2015.08.006. Epub 2015 Aug 10. PubMed PMID: 26412534.

3: Oliveira FA, Reis LP, Soto-Blanco B, Melo MM. Pesticides residues in the Prochilodus costatus (Valenciennes, 1850) fish caught in the São Francisco River, Brazil. J Environ Sci Health B. 2015;50(6):398-405. doi: 10.1080/03601234.2015.1011946. PubMed PMID: 25844860.

4: Ma L, Jia L, Zhou X, Liu Y, Fan X, Pan C. [Analysis of aldicarb and its metabolites in ginger using ultra performance liquid chromatography-tandem mass spectrometry coupled with multiplug filtration clean up with multiwalled carbon nanotubes]. Se Pu. 2014 Jun;32(6):635-9. Chinese. PubMed PMID: 25269263.

5: Yang X, Li P, Zhao Y, Wu Y. [Determination of aldicarb and its metabolites in peanuts by high performance liquid chromatography-linear ion trap triple stage mass spectrometry]. Se Pu. 2012 Mar;30(3):309-13. Chinese. PubMed PMID: 22715699.

6: Bucaretchi F, Prado CC, Branco MM, Soubhia P, Metta GM, Mello SM, de Capitani EM, Lanaro R, Hyslop S, Costa JL, Fernandes LC, Vieira RJ. Poisoning by illegal rodenticides containing acetylcholinesterase inhibitors (chumbinho): a prospective case series. Clin Toxicol (Phila). 2012 Jan;50(1):44-51. doi: 10.3109/15563650.2011.639715. Epub 2011 Dec 19. PubMed PMID: 22175788.

7: Maggio RM, Damiani PC, Olivieri AC. Multivariate curve-resolution analysis of pesticides in water samples from liquid chromatographic-diode array data. Talanta. 2011 Jan 30;83(4):1173-80. doi: 10.1016/j.talanta.2010.06.059. Epub 2010 Jul 24. PubMed PMID: 21215852.

8: Moore DR, Thompson RP, Rodney SI, Fischer D, Ramanarayanan T, Hall T. Refined aquatic risk assessment for aldicarb in the United States. Integr Environ Assess Manag. 2010 Jan;6(1):102-18. doi: 10.1897/IEAM_2009-024.1. PubMed PMID: 20821677.

9: Lu H, Lin Y, Wilson PC. Organic-solvent-free extraction method for determination of carbamate and carbamoyloxime pesticides in soil and sediment samples. Bull Environ Contam Toxicol. 2009 Nov;83(5):621-5. doi: 10.1007/s00128-009-9873-7. PubMed PMID: 19771381.

10: Pelekis M, Emond C. Physiological modeling and derivation of the rat to human toxicokinetic uncertainty factor for the carbamate pesticide aldicarb. Environ Toxicol Pharmacol. 2009 Sep;28(2):179-91. doi: 10.1016/j.etap.2009.04.002. Epub 2009 Apr 11. PubMed PMID: 21784001.

11: Dixit V, Tewari JC, Obendorf SK. Identification of degraded products of aldicarb due to the catalytic behavior of titanium dioxide/polyacrylonitrile nanofiber. J Chromatogr A. 2009 Sep 4;1216(36):6394-9. doi: 10.1016/j.chroma.2009.07.031. Epub 2009 Jul 21. PubMed PMID: 19651412.

12: Totti S, Fernández M, Ghini S, Picó Y, Fini F, Mañes J, Girotti S. Application of matrix solid phase dispersion to the determination of imidacloprid, carbaryl, aldicarb, and their main metabolites in honeybees by liquid chromatography-mass spectrometry detection. Talanta. 2006 May 15;69(3):724-9. doi: 10.1016/j.talanta.2005.11.012. Epub 2005 Dec 20. PubMed PMID: 18970629.

13: Maran E, Fernández M, Barbieri P, Font G, Ruiz MJ. Effects of four carbamate compounds on antioxidant parameters. Ecotoxicol Environ Saf. 2009 Mar;72(3):922-30. doi: 10.1016/j.ecoenv.2008.01.018. Epub 2008 Mar 6. PubMed PMID: 18328561.

14: Fukazawa T, Kobayashi T, Tokairin S, Chimi K, Maruyama T, Yanagita T. [Behavior of N-methylcarbamate pesticides during refinement processing of edible oils]. J Oleo Sci. 2007;56(2):65-71. Japanese. PubMed PMID: 17898465.

15: Jones RL, Allen R. Summary of potable well monitoring conducted for aldicarb and its metabolites in the United States in 2005. Environ Toxicol Chem. 2007 Jul;26(7):1355-60. PubMed PMID: 17665674.

16: Wang J, Wotherspoon D. Determination of pesticides in apples by liquid chromatography with electrospray ionization tandem mass spectrometry and estimation of measurement uncertainty. J AOAC Int. 2007 Mar-Apr;90(2):550-67. PubMed PMID: 17474525.

17: Leandro CC, Hancock P, Fussell RJ, Keely BJ. Ultra-performance liquid chromatography for the determination of pesticide residues in foods by tandem quadrupole mass spectrometry with polarity switching. J Chromatogr A. 2007 Mar 16;1144(2):161-9. Epub 2007 Jan 13. PubMed PMID: 17303144.

18: Küster E, Altenburger R. Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio). Chemosphere. 2007 Jun;68(4):751-60. Epub 2007 Feb 9. PubMed PMID: 17292441.

19: Sinclair CJ, Boxall AB, Parsons SA, Thomas MR. Prioritization of pesticide environmental transformation products in drinking water supplies. Environ Sci Technol. 2006 Dec 1;40(23):7283-9. PubMed PMID: 17180979.

20: Rawn DF, Roscoe V, Trelka R, Hanson C, Krakalovich T, Dabeka RW. N-methyl carbamate pesticide residues in conventional and organic infant foods available on the Canadian retail market, 2001-03. Food Addit Contam. 2006 Jul;23(7):651-9. PubMed PMID: 16751141.