Mazapertine succinate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461581

CAS#: 134208-18-7

Description: Mazapertine succinate is an antipsychotic agent.


Chemical Structure

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Mazapertine succinate
CAS# 134208-18-7

Theoretical Analysis

MedKoo Cat#: 461581
Name: Mazapertine succinate
CAS#: 134208-18-7
Chemical Formula: C30H41N3O6
Exact Mass: 539.2995
Molecular Weight: 539.67
Elemental Analysis: C, 66.77; H, 7.66; N, 7.79; O, 17.79

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Mazapertine succinate; Mazapertine;

IUPAC/Chemical Name: (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone succinate

InChi Key: WAHFGTZTVZRLEY-UHFFFAOYSA-N

InChi Code: InChI=1S/C26H35N3O2.C4H6O4/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29;5-3(6)1-2-4(7)8/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3;1-2H2,(H,5,6)(H,7,8)

SMILES Code: O=C(O)CCC(O)=O.O=C(N1CCCCC1)C2=CC=CC(CN3CCN(C4=CC=CC=C4OC(C)C)CC3)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 539.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Ye N, Song Z, Zhang A. Dual ligands targeting dopamine D2 and serotonin 5-HT1A receptors as new antipsychotical or anti-Parkinsonian agents. Curr Med Chem. 2014;21(4):437-57. Review. PubMed PMID: 24164194.

2: Caldwell GW, Wu WN, McKown LA, Diane Gauthier A, Masucci JA, Jones WJ, Leo GC, Reitz AB. Distribution and metabolism of the antipsychotic agent mazapertine succinate in rats. J Pharm Biomed Anal. 2006 May 3;41(2):500-9. Epub 2005 Dec 28. PubMed PMID: 16386397.

3: Wu WN, McKown LA, Takacs AR, Jones WJ, Reitz AB. Biotransformation of the antipsychotic agent, mazapertine, in dog--mass spectral characterization and identification of metabolites. Xenobiotica. 1999 May;29(5):453-66. PubMed PMID: 10379984.