WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 592747
Description: Alvimopan monohydrate is a mu opioid receptor antagonist; intended to treat constipation in patients taking opiates for pain.
MedKoo Cat#: 592747
Name: Alvimopan monohydrate
Chemical Formula: C25H34N2O5
Exact Mass: 442.2468
Molecular Weight: 442.56
Elemental Analysis: C, 67.85; H, 7.74; N, 6.33; O, 18.08
This product is not in stock, which may be available by custom synthesis.
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Synonym: Alvimopan monohydrate
IUPAC/Chemical Name: ((2S)-2-(((3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-3-phenylpropanoyl)amino)acetic acid monohydrate
InChi Key: XSTFUWQLHMJPFG-NABRLNOVSA-N
InChi Code: InChI=1S/C25H32N2O4.H2O/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19;/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30);1H2/t18-,20-,25+;/m0./s1
SMILES Code: C[C@H]1CN(C[C@@H](C(NCC(O)=O)=O)Cc2ccccc2)CC[C@]1(c3cc(O)ccc3)C.O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 442.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Bayés M, Rabasseda X. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2008 Jan-Feb;30(1):67-99. PubMed PMID: 18389098.