IMB-808
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555294

CAS#: 870768-70-0

Description: IMB-808 is a potent liver X receptor α and β (LXRα/β) partial dual agonist that promotes expression of genes related to reverse cholesterol transport (including ABCA1 and ABCG1).


Chemical Structure

img
IMB-808
CAS# 870768-70-0

Theoretical Analysis

MedKoo Cat#: 555294
Name: IMB-808
CAS#: 870768-70-0
Chemical Formula: C18H15F3N2O4
Exact Mass: 380.10
Molecular Weight: 380.320
Elemental Analysis: C, 56.85; H, 3.98; F, 14.99; N, 7.37; O, 16.83

Price and Availability

Size Price Availability Quantity
50mg USD 550 2 Weeks
100mg USD 950 2 Weeks
200mg USD 1450 2 Weeks
500mg USD 2850 2 Weeks
1g USD 3950 2 Weeks
2g USD 5950 2 Weeks
Bulk inquiry

Synonym: IMB-808; IMB 808; IMB808

IUPAC/Chemical Name: 2,3-Dihydro-N-methyl-N-[2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl]-1,4-benzodioxin-6-carboxamide

InChi Key: XITZPIXICJOKTF-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H15F3N2O4/c1-23(9-15(24)22-12-4-3-11(19)16(20)17(12)21)18(25)10-2-5-13-14(8-10)27-7-6-26-13/h2-5,8H,6-7,9H2,1H3,(H,22,24)

SMILES Code: O=C(C1=CC=C(OCCO2)C2=C1)N(C)CC(NC3=CC=C(F)C(F)=C3F)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 380.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Li N, Wang X, Xu Y, Lin Y, Zhu N, Liu P, Lu D, Si S. Identification of a Novel Liver X Receptor Agonist that Regulates the Expression of Key Cholesterol Homeostasis Genes with Distinct Pharmacological Characteristics. Mol Pharmacol. 2017 Apr;91(4):264-276. doi: 10.1124/mol.116.105213. Epub 2017 Jan 13. PubMed PMID: 28087808.