Zinterol HCl
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563548

CAS#: 38241-28-0

Description: Zinterol HCl is a potent and selective β2-adrenoceptor agonist.


Chemical Structure

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Zinterol HCl
CAS# 38241-28-0

Theoretical Analysis

MedKoo Cat#: 563548
Name: Zinterol HCl
CAS#: 38241-28-0
Chemical Formula: C19H27ClN2O4S
Exact Mass: 414.138
Molecular Weight: 414.94
Elemental Analysis: C, 55.00; H, 6.56; Cl, 8.54; N, 6.75; O, 15.42; S, 7.73

Price and Availability

Size Price Availability Quantity
5.0mg USD 290.0 2 Weeks
25.0mg USD 540.0 2 Weeks
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Synonym: Zinterol hydrochloride; Zinterol HCl;

IUPAC/Chemical Name: N-[5-[2-[(1,1-Dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulphonamide hydrochloride

InChi Key: LVNUBJDWJFOMKH-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H26N2O4S.ClH/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25;/h4-11,18,20-23H,12-13H2,1-3H3;1H

SMILES Code: CS(=O)(NC1=CC(C(O)CNC(C)(C)CC2=CC=CC=C2)=CC=C1O)=O.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 414.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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12: Pabbidi MR, Ji X, Samarel AM, Lipsius SL. Laminin enhances beta(2)-adrenergic receptor stimulation of L-type Ca(2+) current via cytosolic phospholipase A(2) signalling in cat atrial myocytes. J Physiol. 2009 Oct 15;587(Pt 20):4785-97. doi: 10.1113/jphysiol.2009.179226. Epub 2009 Aug 24. PubMed PMID: 19703961; PubMed Central PMCID: PMC2770147.

13: Sato M, Hutchinson DS, Evans BA, Summers RJ. The beta3-adrenoceptor agonist 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)prop yl]amino]ethyl]-phenyl]-benzenesulfonamide (L755507) and antagonist (S)-N-[4-[2-[[3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]-ethyl]phenyl] benzenesulfonamide (L748337) activate different signaling pathways in Chinese hamster ovary-K1 cells stably expressing the human beta3-adrenoceptor. Mol Pharmacol. 2008 Nov;74(5):1417-28. doi: 10.1124/mol.108.046979. Epub 2008 Aug 6. PubMed PMID: 18684840.

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20: Hutchinson DS, Chernogubova E, Sato M, Summers RJ, Bengtsson T. Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor. Naunyn Schmiedebergs Arch Pharmacol. 2006 May;373(2):158-68. Epub 2006 Apr 7. PubMed PMID: 16601951.