Oxadiargyl
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MedKoo CAT#: 461440

CAS#: 39807-15-3

Description: Oxadiargyl is a protoporphyrinogen oxidase inhibitor and is used as a herbicide in China.


Chemical Structure

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Oxadiargyl
CAS# 39807-15-3

Theoretical Analysis

MedKoo Cat#: 461440
Name: Oxadiargyl
CAS#: 39807-15-3
Chemical Formula: C15H14Cl2N2O3
Exact Mass: 340.0381
Molecular Weight: 341.18
Elemental Analysis: Chemical Formula: C15H14Cl2N2O3 Exact Mass: 340.0381 Molecular Weight: 341.1880 Elemental Analysis: C, 52.81; H, 4.14; Cl, 20.78; N, 8.21; O, 14.07

Price and Availability

Size Price Availability Quantity
100.0mg USD 220.0 2 Weeks
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Synonym: Oxadiargyl; Topstar; RP 020630; RP-020630; RP020630;

IUPAC/Chemical Name: 5-(tert-butyl)-3-(2,4-dichloro-5-(prop-2-yn-1-yloxy)phenyl)-1,3,4-oxadiazol-2(3H)-one

InChi Key: DVOODWOZJVJKQR-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H14Cl2N2O3/c1-5-6-21-12-8-11(9(16)7-10(12)17)19-14(20)22-13(18-19)15(2,3)4/h1,7-8H,6H2,2-4H3

SMILES Code: O=C1OC(C(C)(C)C)=NN1C2=CC(OCC#C)=C(Cl)C=C2Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 341.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Mahmoudi M, Rahnemaie R, Es-haghi A, Malakouti MJ. Kinetics of degradation and adsorption-desorption isotherms of thiobencarb and oxadiargyl in calcareous paddy fields. Chemosphere. 2013 May;91(7):1009-17. doi: 10.1016/j.chemosphere.2013.01.077. Epub 2013 Feb 22. PubMed PMID: 23461836.

2: Sanyal N, Alam S, Pradhan S, Banerjee K, Chowdhury A, Aktar MW. Metabolism and dissipation kinetics of a novel protoporphyrinogen IX oxidase herbicide [oxadiargyl] in various buffered aqueous system under laboratory-simulated condition. Environ Monit Assess. 2015 Jul;187(7):433. doi: 10.1007/s10661-015-4345-5. Epub 2015 Jun 16. PubMed PMID: 26077021.

3: Ahmed S, Chauhan BS. Performance of different herbicides in dry-seeded rice in Bangladesh. ScientificWorldJournal. 2014 Feb 6;2014:729418. doi: 10.1155/2014/729418. eCollection 2014. PubMed PMID: 24688423; PubMed Central PMCID: PMC3933028.

4: Es-Haghi A, Baghernejad M, Bagheri H. Novel unbreakable solid-phase microextraction fibers on stainless steel wire and application for the determination of oxadiargyl in environmental and agricultural samples in combination with gas chromatography-mass spectrometry. Talanta. 2014 Oct;128:231-6. doi: 10.1016/j.talanta.2014.04.088. Epub 2014 May 13. PubMed PMID: 25059153.

5: Benfeito S, Rodrigues T, Garrido J, Borges F, Garrido EM. Host-guest interaction between herbicide oxadiargyl and hydroxypropyl-β-cyclodextrin. ScientificWorldJournal. 2013 Nov 25;2013:825206. doi: 10.1155/2013/825206. eCollection 2013. PubMed PMID: 24396310; PubMed Central PMCID: PMC3874296.

6: Shi C, Gui W, Chen J, Zhu G. Determination of oxadiargyl residues in environmental samples and rice samples. Bull Environ Contam Toxicol. 2010 Feb;84(2):236-9. doi: 10.1007/s00128-009-9881-7. Epub 2009 Sep 27. PubMed PMID: 19784803.

7: Singh V, Jat ML, Ganie ZA, Chauhan BS, Gupta RK. Herbicide options for effective weed management in dry direct-seeded rice under scented rice-wheat rotation of western Indo-Gangetic Plains. Crop Prot. 2016 Mar;81:168-176. PubMed PMID: 26941471; PubMed Central PMCID: PMC4767026.

8: Jiang LL, Tan Y, Zhu XL, Wang ZF, Zuo Y, Chen Q, Xi Z, Yang GF. Design, synthesis, and 3D-QSAR analysis of novel 1,3,4-oxadiazol-2(3H)-ones as protoporphyrinogen oxidase inhibitors. J Agric Food Chem. 2010 Mar 10;58(5):2643-51. doi: 10.1021/jf9026298. PubMed PMID: 19954223.

9: Kang G, Kim J, Park H, Kim TH. Crystal structure of oxadiarg-yl. Acta Crystallogr E Crystallogr Commun. 2015 Jun 20;71(Pt 7):o494. doi: 10.1107/S2056989015011524. eCollection 2015 Jul 1. PubMed PMID: 26279926; PubMed Central PMCID: PMC4518994.

10: Ahmed A, Shamsi A, Bano B. Oxadiargyl induced conformational transition of cystatin isolated from yellow mustard seeds: Biophysical and biochemical approach. Int J Biol Macromol. 2017 May;98:802-809. doi: 10.1016/j.ijbiomac.2017.02.055. Epub 2017 Feb 16. PubMed PMID: 28214581.

11: Dayan FE, Meazza G, Bettarini F, Signorini E, Piccardi P, Romagni JG, Duke SO. Synthesis, herbicidal activity, and mode of action of IR 5790. J Agric Food Chem. 2001 May;49(5):2302-7. PubMed PMID: 11368593.

12: Ma J, Wang S, Wang P, Ma L, Chen X, Xu R. Toxicity assessment of 40 herbicides to the green alga Raphidocelis subcapitata. Ecotoxicol Environ Saf. 2006 Mar;63(3):456-62. PubMed PMID: 16406601.

Oxadiargyl

100.0mg / USD 220.0