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MedKoo CAT#: 563472

CAS#: 1090528-71-4

Description: T6167923 is an inhibitor of MyD88-dependent signaling pathways. It acts by disrupting MyD88 homodimeric formation, which is critical for its signaling function.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-02. Prices are subject to change without notice.

T6167923 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 563472
Name: T6167923
CAS#: 1090528-71-4
Chemical Formula: C17H20BrN3O3S2
Exact Mass: 457.0129
Molecular Weight: 458.38
Elemental Analysis: C, 44.54; H, 4.40; Br, 17.43; N, 9.17; O, 10.47; S, 13.99

Synonym: T6167923; T-6167923; T 6167923;

IUPAC/Chemical Name: 4-(3-Bromophenyl)sulfonyl-N-(1-thiophen-2-ylethyl)piperazine-1-carboxamide


InChi Code: InChI=1S/C17H20BrN3O3S2/c1-13(16-6-3-11-25-16)19-17(22)20-7-9-21(10-8-20)26(23,24)15-5-2-4-14(18)12-15/h2-6,11-13H,7-10H2,1H3,(H,19,22)

SMILES Code: O=C(N1CCN(S(=O)(C2=CC=CC(Br)=C2)=O)CC1)NC(C3=CC=CS3)C

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Saqib U, Baig MS. Identifying the inhibition of TIR proteins involved in TLR signalling as an anti-inflammatory strategy. SAR QSAR Environ Res. 2018 Apr;29(4):295-318. doi: 10.1080/1062936X.2018.1431308. Epub 2018 Feb 15. PubMed PMID: 29448819.

2: Olson MA, Lee MS, Kissner TL, Alam S, Waugh DS, Saikh KU. Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen. Sci Rep. 2015 Sep 18;5:14246. doi: 10.1038/srep14246. PubMed PMID: 26381092; PubMed Central PMCID: PMC4585646.