Valofane

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592628

CAS#: 3258-51-3

Description: Valofane is a neurotropic drug.

Chemical Structure

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Valofane
CAS# 3258-51-3
Instruction

Theoretical Analysis

MedKoo Cat#: 592628
Name: Valofane
CAS#: 3258-51-3
Chemical Formula: C10H14N2O4
Exact Mass: 226.10
Molecular Weight: 226.232
Elemental Analysis: C, 53.09; H, 6.24; N, 12.38; O, 28.29

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Valofane

IUPAC/Chemical Name: (3-Allyltetrahydro-5-methyl-2-oxo-3-furoyl)urea

InChi Key: LVJAHKSVOQLCEV-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H14N2O4/c1-3-4-10(7(13)12-9(11)15)5-6(2)16-8(10)14/h3,6H,1,4-5H2,2H3,(H3,11,12,13,15)

SMILES Code: InChI=1S/C10H14N2O4/c1-3-4-10(7(13)12-9(11)15)5-6(2)16-8(10)14/h3,6H,1,4-5H2,2H3,(H3,11,12,13,15)

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 226.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. Eur J Drug Metab Pharmacokinet. 1981;6(3):161-9. PubMed PMID: 6118275.

2: Wittekind HH, Testa B, Balant LP. Isomerisation and urinary excretion of proxibarbal and valofan in man; a preliminary study. Eur J Drug Metab Pharmacokinet. 1984 Apr-Jun;9(2):117-22. PubMed PMID: 6146529.

3: Traversa U, Puppini P, Florio C, Vertua R. Effects of an atypical barbiturate (valofan) on spontaneous and stimulated locomotor activity and on brain serotonin metabolism in mice. Farmaco Sci. 1987 Oct;42(10):755-66. PubMed PMID: 2449358.

4: Lambrey B, Lafont O, D'Athis P, Jacquot C. [Development of proxibarbal blood levels. The role of various elimination processes]. J Pharmacol. 1984 Apr-Jun;15(2):223-30. French. PubMed PMID: 6145815.

5: Traversa U, Florio C, Vertua R. Effects of 2-allophanyl-2-allyl-4-valerolactone (valofan) on cerebral energy metabolism of rat in normoxia and hypobaric hypoxia. In Vivo. 1987 May-Jun;1(3):147-50. PubMed PMID: 2979778.

6: Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. J Pharmacol. 1985 Jul-Sep;16(3):279-90. PubMed PMID: 2415778.