Quazolast

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461299

CAS#: 86048-40-0

Description: Quazolast is a mast cell stabilizer and a potent mediator release inhibitor.

Chemical Structure

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Quazolast
CAS# 86048-40-0
Instruction

Theoretical Analysis

MedKoo Cat#: 461299
Name: Quazolast
CAS#: 86048-40-0
Chemical Formula: C12H7ClN2O3
Exact Mass: 262.01
Molecular Weight: 262.640
Elemental Analysis: C, 54.88; H, 2.69; Cl, 13.50; N, 10.67; O, 18.27

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Quazolast; RHC 3988; RHC-3988; RHC3988;

IUPAC/Chemical Name: methyl 5-chlorooxazolo[4,5-h]quinoline-2-carboxylate

InChi Key: ZCRBUWNCWCWRGL-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H7ClN2O3/c1-17-12(16)11-15-8-5-7(13)6-3-2-4-14-9(6)10(8)18-11/h2-5H,1H3

SMILES Code: O=C(C1=NC2=CC(Cl)=C3C=CC=NC3=C2O1)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 262.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Reconstitution Calculator

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Dilution Calculator

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1: Fitzpatrick LR, Decktor DL. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6. PubMed PMID: 1683105.

2: Dave NK, McMahon SC, Grubbe RE, Bewtra AK, Hopp RJ, Nair NM, Smith J, Townley RG. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302. PubMed PMID: 2221488.